Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2486778..2486962 Replicon chromosome
Accession NZ_AP017891
Organism Staphylococcus aureus strain GN3

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CTB89_RS12750 Protein ID WP_000482647.1
Coordinates 2486855..2486962 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2486778..2486838 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTB89_RS12730 2482288..2482455 - 168 WP_001789205.1 hypothetical protein -
CTB89_RS12740 2482686..2484419 - 1734 WP_020977552.1 ABC transporter ATP-binding protein/permease -
CTB89_RS12745 2484444..2486207 - 1764 WP_001064822.1 ABC transporter ATP-binding protein/permease -
CTB89_RS14415 2486661..2486828 - 168 WP_000301893.1 hypothetical protein -
- 2486778..2486838 + 61 - - Antitoxin
CTB89_RS12750 2486855..2486962 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CTB89_RS12755 2487096..2487482 - 387 WP_000779353.1 flippase GtxA -
CTB89_RS12760 2487750..2488892 + 1143 WP_001176863.1 glycerate kinase -
CTB89_RS12765 2488952..2489611 + 660 WP_000831298.1 membrane protein -
CTB89_RS12770 2489794..2491005 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
CTB89_RS12775 2491128..2491601 - 474 WP_020977553.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T31349 WP_000482647.1 NZ_AP017891:c2486962-2486855 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T31349 NZ_AP017891:c2486962-2486855 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT31349 NZ_AP017891:2486778-2486838 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References