Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2281942..2282159 Replicon chromosome
Accession NZ_AP017891
Organism Staphylococcus aureus strain GN3

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CTB89_RS11635 Protein ID WP_001802298.1
Coordinates 2282055..2282159 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2281942..2281997 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTB89_RS11615 2278075..2278740 - 666 WP_001024095.1 SDR family oxidoreductase -
CTB89_RS11620 2278892..2279212 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CTB89_RS11625 2279214..2280191 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
CTB89_RS11630 2280457..2281548 + 1092 WP_020977458.1 hypothetical protein -
- 2281942..2281997 + 56 - - Antitoxin
CTB89_RS11635 2282055..2282159 - 105 WP_001802298.1 hypothetical protein Toxin
CTB89_RS14330 2282320..2282823 - 504 Protein_2158 recombinase family protein -
CTB89_RS11645 2282871..2284163 + 1293 WP_020977460.1 IS21 family transposase -
CTB89_RS11650 2284156..2284917 + 762 WP_001066124.1 IS21-like element helper ATPase IstB -
CTB89_RS14395 2285053..2286189 - 1137 Protein_2161 SAP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2284156..2284917 761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31346 WP_001802298.1 NZ_AP017891:c2282159-2282055 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31346 NZ_AP017891:c2282159-2282055 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT31346 NZ_AP017891:2281942-2281997 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References