Detailed information of TA system TA031340

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1970890..1971070
• Replicon: chromosome
• Accession: NZ_AP017891
• Organism: Staphylococcus aureus strain GN3

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CTB89_RS09800
• Protein ID: WP_001801861.1
• Coordinates: 1970890..1970985 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1971013..1971070 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTB89_RS09755	1966354..1967352	+	999	WP_120173197.1	DUF4352 domain-containing protein	-
CTB89_RS09760	1967428..1968054	+	627	WP_000669045.1	hypothetical protein	-
CTB89_RS09765	1968095..1968436	+	342	WP_000627534.1	DUF3969 family protein	-
CTB89_RS09770	1968537..1969109	+	573	WP_000414218.1	hypothetical protein	-
CTB89_RS09775	1969439..1969624	-	186	WP_000809860.1	hypothetical protein	-
CTB89_RS09780	1969626..1969802	-	177	WP_000375478.1	hypothetical protein	-
CTB89_RS09785	1969813..1970102	-	290	Protein_1848	hypothetical protein	-
CTB89_RS09790	1970270..1970503	-	234	Protein_1849	IS3 family transposase	-
CTB89_RS09795	1970509..1970745	-	237	WP_000251969.1	IS3 family transposase	-
CTB89_RS09800	1970890..1970985	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1971013..1971070	-	58	-	-	Antitoxin
CTB89_RS14380	1971201..1971356	+	156	WP_001215823.1	hypothetical protein	-
CTB89_RS09810	1971926..1972368	-	443	Protein_1853	DUF1433 domain-containing protein	-
CTB89_RS09815	1972368..1972811	-	444	WP_000731420.1	DUF1433 domain-containing protein	-
CTB89_RS09820	1972811..1973254	-	444	WP_000747798.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1970509..1970745	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T31340 WP_001801861.1 NZ_AP017891:1970890-1970985 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T31340 NZ_AP017891:1970890-1970985 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT31340 NZ_AP017891:c1971070-1971013 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin