Detailed information of TA system TA031208

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 3937525..3937747
• Replicon: chromosome
• Accession: NZ_AP017610
• Organism: Escherichia coli strain 20Ec-P-124

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: CPZ02_RS20365
• Protein ID: WP_001295224.1
• Coordinates: 3937525..3937632 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	3937689..3937747 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPZ02_RS20340	3932778..3933530	-	753	WP_000279544.1	cellulose biosynthesis protein BcsQ	-
CPZ02_RS20345	3933542..3933730	-	189	WP_001063315.1	YhjR family protein	-
CPZ02_RS20350	3934003..3935574	+	1572	WP_001204944.1	cellulose biosynthesis protein BcsE	-
CPZ02_RS20355	3935571..3935762	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
CPZ02_RS20360	3935759..3937438	+	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
CPZ02_RS20365	3937525..3937632	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	3937689..3937747	+	59	-	-	Antitoxin
CPZ02_RS28765	3938008..3938115	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
CPZ02_RS20385	3938591..3939862	+	1272	WP_001318103.1	amino acid permease	-
CPZ02_RS20390	3939892..3940896	-	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
CPZ02_RS20395	3940893..3941876	-	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T31208 WP_001295224.1 NZ_AP017610:c3937632-3937525 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T31208 NZ_AP017610:c3937632-3937525 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT31208 NZ_AP017610:3937689-3937747 [Escherichia coli]
TCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin