Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1101128..1101632 Replicon chromosome
Accession NZ_AP017560
Organism Pseudanabaena sp. ABRG5-3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ABRG53_RS05015 Protein ID WP_126385617.1
Coordinates 1101128..1101385 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ABRG53_RS05020 Protein ID WP_126385618.1
Coordinates 1101369..1101632 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABRG53_RS04980 1096228..1096500 - 273 WP_126385610.1 TMEM165/GDT1 family protein -
ABRG53_RS04985 1096565..1096930 - 366 WP_126385611.1 TMEM165/GDT1 family protein -
ABRG53_RS04990 1097122..1097751 - 630 WP_126385612.1 class I SAM-dependent methyltransferase -
ABRG53_RS04995 1097748..1098170 - 423 WP_126385613.1 acyl-CoA thioesterase -
ABRG53_RS05000 1098211..1099245 - 1035 WP_126385614.1 3-deoxy-7-phosphoheptulonate synthase -
ABRG53_RS05005 1099391..1099669 - 279 WP_126385615.1 hypothetical protein -
ABRG53_RS25390 1099798..1099950 - 153 WP_162615614.1 hypothetical protein -
ABRG53_RS05010 1100147..1101022 + 876 WP_126385616.1 lipoyl synthase -
ABRG53_RS25395 1100971..1101135 - 165 WP_162615615.1 hypothetical protein -
ABRG53_RS05015 1101128..1101385 - 258 WP_126385617.1 Txe/YoeB family addiction module toxin Toxin
ABRG53_RS05020 1101369..1101632 - 264 WP_126385618.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ABRG53_RS05025 1101782..1102235 - 454 Protein_999 HNH endonuclease -
ABRG53_RS05030 1102243..1102482 - 240 WP_126385619.1 hypothetical protein -
ABRG53_RS05035 1102624..1103180 - 557 Protein_1001 DUF3782 domain-containing protein -
ABRG53_RS05040 1103414..1103719 + 306 WP_126385620.1 helix-turn-helix domain-containing protein -
ABRG53_RS05045 1103725..1104078 - 354 WP_126385621.1 type II toxin-antitoxin system RelE/ParE family toxin -
ABRG53_RS05050 1104075..1104590 - 516 WP_126385622.1 DUF2726 domain-containing protein -
ABRG53_RS05055 1104626..1105435 - 810 WP_126385623.1 hypothetical protein -
ABRG53_RS05060 1105581..1105901 - 321 WP_126385624.1 RNA-binding protein -
ABRG53_RS05065 1105901..1106122 - 222 WP_126385625.1 type II toxin-antitoxin system HicB family antitoxin -
ABRG53_RS05070 1106253..1106555 - 303 WP_126385626.1 HigA family addiction module antidote protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(25-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10158.80 Da        Isoelectric Point: 10.5022

>T31151 WP_126385617.1 NZ_AP017560:c1101385-1101128 [Pseudanabaena sp. ABRG5-3]
MQWKIEFSRNVIRDAKKLKFANLDSNLKSLLEILKRNPYEPPYEKLSGNLKGYLSRRINIKHRLVYSVHDEAKTVRVVSV
WSHYE

Download         Length: 258 bp

>T31151 NZ_AP017560:c1101385-1101128 [Pseudanabaena sp. ABRG5-3]
ATGCAATGGAAGATTGAATTTAGTCGGAATGTGATTAGAGATGCAAAAAAATTAAAGTTTGCTAATTTGGACTCTAACCT
CAAATCTTTACTAGAAATTCTCAAACGAAATCCTTATGAACCTCCCTATGAAAAACTTTCAGGCAACTTGAAAGGATATT
TATCAAGAAGAATCAATATCAAACATCGTTTGGTTTATTCAGTCCATGATGAAGCTAAAACTGTTCGAGTTGTTTCTGTA
TGGTCACATTATGAGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9822.95 Da        Isoelectric Point: 4.0414

>AT31151 WP_126385618.1 NZ_AP017560:c1101632-1101369 [Pseudanabaena sp. ABRG5-3]
MKILNASEARANLFSLVEQVNKDHLPRFITSRQGDAVLLSKSDWESIQETLYLQSIPNLVESIRAAEQADDWVSEDEFLG
ALNAMED

Download         Length: 264 bp

>AT31151 NZ_AP017560:c1101632-1101369 [Pseudanabaena sp. ABRG5-3]
ATGAAAATTCTCAATGCGAGTGAAGCGAGAGCCAACTTATTCAGCTTAGTCGAGCAAGTTAATAAAGATCATTTGCCAAG
ATTTATTACAAGTCGGCAAGGTGACGCAGTATTGCTATCTAAATCTGATTGGGAGAGCATACAAGAAACCCTCTATCTAC
AATCTATCCCTAATTTAGTTGAGTCAATAAGAGCCGCAGAACAAGCAGATGATTGGGTTTCTGAAGATGAATTTCTTGGA
GCCTTGAATGCAATGGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References