Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4257823..4258519 Replicon chromosome
Accession NZ_AP017469
Organism Hafnia sp. CBA7124

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag CPY98_RS19335 Protein ID WP_096388622.1
Coordinates 4258208..4258519 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag CPY98_RS19330 Protein ID WP_043489471.1
Coordinates 4257823..4258221 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPY98_RS19320 4253519..4255966 + 2448 WP_096388621.1 glycogen phosphorylase -
CPY98_RS19325 4256096..4257580 - 1485 WP_025799362.1 glycerol-3-phosphate dehydrogenase -
CPY98_RS19330 4257823..4258221 - 399 WP_043489471.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CPY98_RS19335 4258208..4258519 - 312 WP_096388622.1 type II toxin-antitoxin system MqsR family toxin Toxin
CPY98_RS19340 4258775..4259533 - 759 WP_025799366.1 DeoR/GlpR family transcriptional regulator -
CPY98_RS19345 4259580..4260416 - 837 WP_043489475.1 rhomboid family intramembrane serine protease GlpG -
CPY98_RS19350 4260464..4260793 - 330 WP_096388623.1 thiosulfate sulfurtransferase GlpE -
CPY98_RS19355 4261067..4261498 + 432 WP_043489478.1 hypothetical protein -
CPY98_RS19360 4261634..4262392 - 759 WP_025799373.1 glycerophosphodiester phosphodiesterase -
CPY98_RS19365 4262426..4263502 - 1077 WP_096388624.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12026.03 Da        Isoelectric Point: 8.2604

>T31145 WP_096388622.1 NZ_AP017469:c4258519-4258208 [Hafnia sp. CBA7124]
MEKRTPHCSLEKVRSLIGKGMIKATKVAYLNAKRLDFSCADMYRVVSELSAKDFYKSMTTYQNHKIWQDVYHCHLEKVSL
YLKLTVVDEVLIVSFKELDDDMS

Download         Length: 312 bp

>T31145 NZ_AP017469:c4258519-4258208 [Hafnia sp. CBA7124]
ATGGAGAAGCGAACGCCGCATTGTAGCTTGGAAAAGGTACGGAGTTTGATTGGGAAGGGGATGATTAAAGCCACAAAAGT
CGCTTATTTGAATGCGAAGCGCCTCGATTTTAGCTGTGCAGATATGTATCGAGTCGTGAGTGAGTTATCTGCTAAAGACT
TTTATAAAAGTATGACAACGTATCAAAACCACAAAATTTGGCAGGATGTGTACCACTGCCATCTGGAAAAGGTATCTCTC
TATCTGAAACTAACGGTAGTGGATGAAGTGTTAATCGTGTCTTTTAAGGAGCTAGATGATGATATGTCCTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14872.07 Da        Isoelectric Point: 4.9755

>AT31145 WP_043489471.1 NZ_AP017469:c4258221-4257823 [Hafnia sp. CBA7124]
MICPECGSSNTVKEYRDTPYTYKGQTMIIKAWGADWCLDCGEGVIFKEESLRIDSILTEFNKQVNASIIDPEYVVAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLEEIRN

Download         Length: 399 bp

>AT31145 NZ_AP017469:c4258221-4257823 [Hafnia sp. CBA7124]
ATGATATGTCCTGAATGTGGATCGTCCAACACGGTGAAGGAGTACCGTGATACTCCCTACACCTATAAAGGCCAAACGAT
GATAATCAAGGCATGGGGCGCTGACTGGTGTTTAGACTGCGGGGAAGGTGTGATTTTTAAAGAAGAATCTCTGCGTATCG
ACAGCATTTTGACGGAGTTCAACAAGCAGGTTAATGCTTCCATCATCGATCCTGAGTACGTGGTGGCAATGCGAAAAAAG
CTGAACCTTTCCCAAAGTGAAGCCGGTGAGATCTTTGGCGGCGGTGTGAACGCATTTTCGCGCTACGAAACAGGCAAAGC
GCTGCCCCATGTATCGACCATCAAGTTGTTAAAATTGCTTGATAAATATCCAGAATTGCTCGAAGAAATTCGTAACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References