Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 474122..474385 Replicon chromosome
Accession NZ_AP017469
Organism Hafnia sp. CBA7124

Toxin (Protein)


Gene name hokH Uniprot ID A0A1C6YY26
Locus tag CPY98_RS02165 Protein ID WP_025798685.1
Coordinates 474227..474385 (+) Length 53 a.a.

Antitoxin (RNA)


Gene name sokH
Locus tag -
Coordinates 474122..474174 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPY98_RS02145 469337..470407 - 1071 WP_043490618.1 dihydroxyacetone kinase subunit DhaK -
CPY98_RS02150 470507..471607 - 1101 WP_043490621.1 glycerol dehydrogenase -
CPY98_RS02155 472113..472796 + 684 WP_043490623.1 DUF1190 family protein -
CPY98_RS02160 472799..473959 + 1161 WP_043490625.1 glutathionylspermidine synthase family protein -
- 474122..474174 - 53 - - Antitoxin
CPY98_RS02165 474227..474385 + 159 WP_025798685.1 Hok/Gef family protein Toxin
CPY98_RS02170 474546..476765 - 2220 WP_025798687.1 lysine decarboxylase -
CPY98_RS02175 476871..478199 - 1329 WP_025798689.1 cadaverine/lysine antiporter -
CPY98_RS02180 478847..479089 + 243 WP_096386189.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-46)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6065.37 Da        Isoelectric Point: 9.2226

>T31129 WP_025798685.1 NZ_AP017469:474227-474385 [Hafnia sp. CBA7124]
MSRKLLLYGLIVMCFTLLIFTWMVRGSLCELRIKQGKTEVAAFLNYEDKHAL

Download         Length: 159 bp

>T31129 NZ_AP017469:474227-474385 [Hafnia sp. CBA7124]
ATGTCGCGTAAGCTGTTGCTTTACGGATTAATAGTGATGTGTTTTACGCTATTGATCTTTACCTGGATGGTACGTGGTTC
GCTGTGTGAGCTACGAATTAAGCAGGGAAAAACAGAGGTTGCCGCGTTCTTAAACTACGAAGATAAGCACGCGTTGTAA

Antitoxin


Download         Length: 53 bp

>AT31129 NZ_AP017469:c474174-474122 [Hafnia sp. CBA7124]
GATGTGGTTAGGATTGCCTCAGGTTAATGAAAATTGACCTGGGGCTTTTACTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C6YY26

Antitoxin

Download structure file

References