Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2579583..2579767 Replicon chromosome
Accession NZ_AP017377
Organism Staphylococcus aureus strain OC8

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag ATE38_RS13585 Protein ID WP_000482650.1
Coordinates 2579660..2579767 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2579583..2579643 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATE38_RS13560 2575113..2575280 - 168 WP_001790576.1 hypothetical protein -
ATE38_RS13570 2575511..2577244 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ATE38_RS13575 2577269..2579032 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2579583..2579643 + 61 - - Antitoxin
ATE38_RS13585 2579660..2579767 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
ATE38_RS13590 2579901..2580287 - 387 WP_000779358.1 flippase GtxA -
ATE38_RS13595 2580555..2581697 + 1143 WP_001176863.1 glycerate kinase -
ATE38_RS13600 2581757..2582416 + 660 WP_000831298.1 membrane protein -
ATE38_RS13605 2582598..2583809 + 1212 WP_001192076.1 multidrug effflux MFS transporter -
ATE38_RS13610 2583932..2584405 - 474 WP_096377502.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T31120 WP_000482650.1 NZ_AP017377:c2579767-2579660 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T31120 NZ_AP017377:c2579767-2579660 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT31120 NZ_AP017377:2579583-2579643 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References