Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2289173..2289436 Replicon chromosome
Accession NZ_AP017377
Organism Staphylococcus aureus strain OC8

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ATE38_RS12010 Protein ID WP_001802298.1
Coordinates 2289332..2289436 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2289173..2289337 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATE38_RS11990 2285356..2286021 - 666 WP_001024094.1 SDR family oxidoreductase -
ATE38_RS11995 2286173..2286493 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ATE38_RS12000 2286495..2287475 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ATE38_RS12005 2287741..2288832 + 1092 WP_000495671.1 lytic regulatory protein -
- 2289173..2289337 + 165 - - Antitoxin
ATE38_RS12010 2289332..2289436 - 105 WP_001802298.1 hypothetical protein Toxin
ATE38_RS15270 2289597..2290080 - 484 Protein_2230 recombinase family protein -
ATE38_RS12020 2290123..2291259 - 1137 WP_000115564.1 SAP domain-containing protein -
ATE38_RS12025 2291548..2291640 + 93 WP_001790138.1 hypothetical protein -
ATE38_RS12030 2292345..2293202 - 858 WP_096377499.1 Cof-type HAD-IIB family hydrolase -
ATE38_RS12035 2293270..2294052 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31117 WP_001802298.1 NZ_AP017377:c2289436-2289332 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31117 NZ_AP017377:c2289436-2289332 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT31117 NZ_AP017377:2289173-2289337 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References