Detailed information of TA system TA031106

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 916955..917137
• Replicon: chromosome
• Accession: NZ_AP017377
• Organism: Staphylococcus aureus strain OC8

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ATE38_RS15230
• Protein ID: WP_001801861.1
• Coordinates: 917042..917137 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	916955..917014 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATE38_RS04630	912176..912769	+	594	WP_000035058.1	peptidylprolyl isomerase	-
ATE38_RS04635	912976..914148	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
ATE38_RS04640	914250..915572	+	1323	Protein_861	ATP-binding protein	-
ATE38_RS04645	916093..916470	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
ATE38_RS04650	916664..916840	+	177	Protein_863	transposase	-
ATE38_RS04655	916818..916919	-	102	WP_001791893.1	hypothetical protein	-
-	916955..917014	+	60	-	-	Antitoxin
ATE38_RS15230	917042..917137	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
ATE38_RS04660	917340..917483	+	144	WP_001549059.1	transposase	-
ATE38_RS04670	918087..918470	+	384	WP_000070811.1	hypothetical protein	-
ATE38_RS04675	918481..918657	+	177	WP_000375476.1	hypothetical protein	-
ATE38_RS04680	918659..918844	+	186	WP_000809857.1	hypothetical protein	-
ATE38_RS04685	918958..919599	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
ATE38_RS04690	919849..921021	+	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
ATE38_RS04695	921149..921700	-	552	WP_000414205.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	912976..914148	1172
	-	flank	IS/Tn	-	-	919849..921021	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T31106 WP_001801861.1 NZ_AP017377:c917137-917042 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T31106 NZ_AP017377:c917137-917042 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT31106 NZ_AP017377:916955-917014 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin