Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2259278..2259494 Replicon chromosome
Accession NZ_AP017320
Organism Staphylococcus aureus strain MI

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAMI_RS11565 Protein ID WP_001802298.1
Coordinates 2259390..2259494 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2259278..2259333 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMI_RS11545 2255484..2256149 - 666 WP_001024095.1 SDR family oxidoreductase -
SAMI_RS11550 2256301..2256621 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAMI_RS11555 2256623..2257600 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SAMI_RS11560 2257866..2258957 + 1092 WP_000495669.1 hypothetical protein -
- 2259278..2259333 + 56 - - Antitoxin
SAMI_RS11565 2259390..2259494 - 105 WP_001802298.1 hypothetical protein Toxin
SAMI_RS15435 2260174..2260332 + 159 WP_001792784.1 hypothetical protein -
SAMI_RS11570 2260990..2261847 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
SAMI_RS11575 2261915..2262697 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31083 WP_001802298.1 NZ_AP017320:c2259494-2259390 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31083 NZ_AP017320:c2259494-2259390 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT31083 NZ_AP017320:2259278-2259333 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References