Detailed information of TA system TA031075

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1932589..1932769
• Replicon: chromosome
• Accession: NZ_AP017320
• Organism: Staphylococcus aureus strain MI

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAMI_RS15680
• Protein ID: WP_001801861.1
• Coordinates: 1932589..1932684 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1932712..1932769 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAMI_RS09590	1927752..1928402	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAMI_RS09595	1928483..1929478	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAMI_RS09600	1929553..1930179	+	627	WP_000669024.1	hypothetical protein	-
SAMI_RS09605	1930220..1930561	+	342	WP_000627540.1	DUF3969 family protein	-
SAMI_RS09610	1930662..1931234	+	573	WP_000414216.1	hypothetical protein	-
SAMI_RS15320	1931432..1932444	-	1013	Protein_1850	IS3 family transposase	-
SAMI_RS15680	1932589..1932684	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1932712..1932769	-	58	-	-	Antitoxin
SAMI_RS09630	1932807..1932908	+	102	WP_001792025.1	hypothetical protein	-
SAMI_RS15685	1932886..1933047	-	162	Protein_1853	transposase	-
SAMI_RS09635	1933038..1933532	-	495	Protein_1854	transposase	-
SAMI_RS09640	1933984..1935213	-	1230	WP_000072627.1	restriction endonuclease subunit S	-
SAMI_RS09645	1935206..1936762	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
SAMI_RS09650	1936912..1937046	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1926994..1992166	65172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T31075 WP_001801861.1 NZ_AP017320:1932589-1932684 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T31075 NZ_AP017320:1932589-1932684 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT31075 NZ_AP017320:c1932769-1932712 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin