Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2131475..2131983 Replicon chromosome
Accession NZ_AP017315
Organism Microcella alkaliphila strain JAM-AC0309

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CPY97_RS10495 Protein ID WP_197702280.1
Coordinates 2131735..2131983 (+) Length 83 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CPY97_RS10490 Protein ID WP_096422528.1
Coordinates 2131475..2131726 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPY97_RS10465 2126748..2127140 - 393 WP_096422520.1 pilus assembly protein -
CPY97_RS13560 2127188..2127364 - 177 WP_173826884.1 hypothetical protein -
CPY97_RS10470 2127445..2128383 - 939 WP_096423609.1 type II secretion system F family protein -
CPY97_RS10475 2128380..2129243 - 864 WP_096422522.1 type II secretion system F family protein -
CPY97_RS10480 2129240..2130481 - 1242 WP_096422524.1 CpaF family protein -
CPY97_RS10485 2130587..2131399 + 813 WP_096422526.1 acetoacetate decarboxylase family protein -
CPY97_RS10490 2131475..2131726 + 252 WP_096422528.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CPY97_RS10495 2131735..2131983 + 249 WP_197702280.1 Txe/YoeB family addiction module toxin Toxin
CPY97_RS10500 2132046..2132246 - 201 WP_096422532.1 hypothetical protein -
CPY97_RS13320 2132743..2133819 - 1077 WP_161494117.1 hypothetical protein -
CPY97_RS10505 2134039..2135397 - 1359 WP_096422534.1 glutamine synthetase family protein -
CPY97_RS10510 2135610..2136326 + 717 WP_096422536.1 type 1 glutamine amidotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9711.05 Da        Isoelectric Point: 8.4793

>T31070 WP_197702280.1 NZ_AP017315:2131735-2131983 [Microcella alkaliphila]
MAFDAHGWEDYVYWQRQDRKTLKRINTLIADVLRDPFAGIGKPEPLKHVLSGAWSRRIDDTNRLVYYVTDEHIVILQARA
HY

Download         Length: 249 bp

>T31070 NZ_AP017315:2131735-2131983 [Microcella alkaliphila]
CTGGCGTTCGACGCCCACGGCTGGGAAGACTACGTCTACTGGCAGCGCCAAGATCGTAAGACGCTGAAGCGCATCAACAC
CCTGATCGCCGACGTGCTTCGTGATCCTTTTGCCGGGATCGGCAAGCCCGAGCCACTCAAGCACGTGCTGTCGGGCGCCT
GGTCTCGCCGAATCGACGACACCAACCGGCTCGTGTACTACGTCACCGACGAGCACATCGTGATTCTGCAGGCGCGGGCG
CACTACTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9121.23 Da        Isoelectric Point: 5.5311

>AT31070 WP_096422528.1 NZ_AP017315:2131475-2131726 [Microcella alkaliphila]
MTAISASEARKTLFGIIQQVNDDHAPVEVVSKHGNAVILSKADYDAMAETAHLLRNPANAERLLASIERARRGEFEQHDL
VDP

Download         Length: 252 bp

>AT31070 NZ_AP017315:2131475-2131726 [Microcella alkaliphila]
ATGACCGCGATCAGTGCATCCGAAGCGCGAAAGACGCTCTTTGGGATCATCCAGCAGGTGAACGACGACCATGCGCCCGT
TGAAGTGGTGTCGAAGCACGGCAACGCCGTCATTCTGTCGAAGGCCGACTATGACGCGATGGCCGAGACCGCCCACCTAC
TGCGGAACCCTGCCAACGCCGAGCGGCTGCTCGCGTCGATCGAGCGCGCCCGGCGCGGAGAGTTCGAGCAGCACGACCTC
GTCGACCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References