Detailed information of TA system TA031068

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 212977..213482
• Replicon: chromosome
• Accession: NZ_AP017313
• Organism: Mucilaginibacter gotjawali strain SA3-7

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: MgSA37_RS01110
• Protein ID: WP_096349440.1
• Coordinates: 212977..213231 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: MgSA37_RS01115
• Protein ID: WP_096349441.1
• Coordinates: 213228..213482 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MgSA37_RS01090	207988..208539	+	552	WP_096349436.1	sigma-70 family RNA polymerase sigma factor	-
MgSA37_RS01095	208549..209373	+	825	WP_096349437.1	anti-sigma factor	-
MgSA37_RS01100	209686..211191	-	1506	WP_096349438.1	NAD(P)H-hydrate dehydratase	-
MgSA37_RS01105	211287..212948	-	1662	WP_096349439.1	peptidase S41	-
MgSA37_RS01110	212977..213231	-	255	WP_096349440.1	Txe/YoeB family addiction module toxin	Toxin
MgSA37_RS01115	213228..213482	-	255	WP_096349441.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
MgSA37_RS01120	213550..216396	-	2847	WP_096349442.1	excinuclease ABC subunit UvrA	-
MgSA37_RS01125	216651..217436	-	786	WP_096349443.1	lytic transglycosylase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10165.82 Da
• Isoelectric Point: 9.3799

>T31068 WP_096349440.1 NZ_AP017313:c213231-212977 [Mucilaginibacter gotjawali]
MKIVFLDQAWDDYLYWQNTDKAMVKKVNSLVKEIERIPFEGSGKPEPLKHNLAGWWSRRITLEHRLVYKIDKDSIVILQC
RYHY

Nucleotide

• Length: 255 bp

>T31068 NZ_AP017313:c213231-212977 [Mucilaginibacter gotjawali]
ATGAAGATCGTTTTTCTGGACCAGGCATGGGATGATTACCTGTATTGGCAAAATACAGACAAAGCCATGGTAAAAAAAGT
CAATTCACTGGTAAAAGAAATTGAACGCATTCCATTTGAAGGCAGCGGGAAACCCGAGCCCTTAAAACATAACCTTGCCG
GCTGGTGGTCCAGGCGAATAACTTTGGAGCACAGGTTGGTATATAAAATTGATAAGGATTCGATCGTTATTCTTCAATGC
CGGTATCATTATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9679.94 Da
• Isoelectric Point: 7.0092

>AT31068 WP_096349441.1 NZ_AP017313:c213482-213228 [Mucilaginibacter gotjawali]
MQVTTYTSFRQKLKSYLDKVRNNHTPLYVTSANGEDVVVLSKSDYESMEETFYLLKSPANASRLLQGIEAYEKGLGKERR
LIEE

Nucleotide

• Length: 255 bp

>AT31068 NZ_AP017313:c213482-213228 [Mucilaginibacter gotjawali]
ATGCAGGTTACAACTTACACAAGTTTCCGCCAGAAGTTAAAATCCTATTTGGATAAAGTTCGGAATAACCATACACCACT
TTATGTGACGAGTGCAAATGGCGAAGATGTTGTAGTACTTTCAAAATCCGACTATGAAAGCATGGAAGAAACATTTTATC
TGCTTAAAAGCCCCGCAAATGCTTCACGGCTATTACAAGGCATTGAAGCCTATGAAAAAGGGTTAGGTAAAGAAAGAAGG
CTTATAGAAGAATGA