Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 999426..999588 Replicon chromosome
Accession NZ_AP014956
Organism Staphylococcus capitis strain TW2795

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A507SQ11
Locus tag JMUB0001_RS04910 Protein ID WP_030063529.1
Coordinates 999426..999530 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 999558..999588 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMUB0001_RS04900 995358..998297 + 2940 WP_070862416.1 AAA family ATPase -
JMUB0001_RS04905 998294..999235 + 942 WP_096389221.1 3'-5' exoribonuclease YhaM -
JMUB0001_RS04910 999426..999530 + 105 WP_030063529.1 type I toxin-antitoxin system Fst family toxin Toxin
- 999558..999588 + 31 - - Antitoxin
JMUB0001_RS04915 999685..1000686 - 1002 WP_023350053.1 peptidylprolyl isomerase -
JMUB0001_RS04920 1000888..1001457 - 570 WP_002434864.1 DUF3267 domain-containing protein -
JMUB0001_RS04925 1001649..1002020 - 372 WP_049428031.1 YtxH domain-containing protein -
JMUB0001_RS04930 1002098..1002523 - 426 WP_049428034.1 HIT family protein -
JMUB0001_RS04935 1002656..1003396 + 741 WP_002453567.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3963.74 Da        Isoelectric Point: 10.7588

>T31041 WP_030063529.1 NZ_AP014956:999426-999530 [Staphylococcus capitis]
MLFDIFVHIMATATSGCIVALFAHWLRTRNDKRK

Download         Length: 105 bp

>T31041 NZ_AP014956:999426-999530 [Staphylococcus capitis]
ATGTTATTTGATATCTTTGTACACATCATGGCCACGGCAACCAGTGGTTGTATCGTTGCTTTATTCGCGCATTGGCTACG
CACTCGCAACGATAAACGTAAATAG

Antitoxin


Download         Length: 31 bp

>AT31041 NZ_AP014956:999558-999588 [Staphylococcus capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A507SQ11


Antitoxin

Download structure file

References