31037

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 278029..278548 Replicon chromosome
Accession NZ_AP014956
Organism Staphylococcus capitis strain TW2795

Toxin (Protein)


Gene name yoeB Uniprot ID A0A507SVT5
Locus tag JMUB0001_RS01210 Protein ID WP_002436254.1
Coordinates 278029..278298 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1J4EAU6
Locus tag JMUB0001_RS01215 Protein ID WP_002436168.1
Coordinates 278291..278548 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMUB0001_RS01190 273082..274893 + 1812 WP_096389097.1 YSIRK-type signal peptide-containing protein -
JMUB0001_RS01195 275007..275765 + 759 WP_030059220.1 esterase family protein -
JMUB0001_RS01200 276308..277456 + 1149 WP_172969460.1 CapA family protein -
JMUB0001_RS01205 277520..277885 - 366 WP_002436243.1 DUF4870 domain-containing protein -
JMUB0001_RS01210 278029..278298 - 270 WP_002436254.1 Txe/YoeB family addiction module toxin Toxin
JMUB0001_RS01215 278291..278548 - 258 WP_002436168.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JMUB0001_RS01220 278733..279590 + 858 WP_002454139.1 ABC transporter substrate-binding protein -
JMUB0001_RS01225 279700..281340 - 1641 WP_030059216.1 alpha-keto acid decarboxylase family protein -
JMUB0001_RS01230 281513..281968 + 456 WP_002436214.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10524.00 Da        Isoelectric Point: 9.7885

>T31037 WP_002436254.1 NZ_AP014956:c278298-278029 [Staphylococcus capitis]
MSKFSVTFTAQAFKDYQYWQQHNQNYFKKVNALLKSIARDGCVDGIGKPEALKGNYEGYFSRRVSIEHRLIYKIKDDSIF
VVSCRFHYQ

Download         Length: 270 bp

>T31037 NZ_AP014956:c278298-278029 [Staphylococcus capitis]
ATGAGTAAGTTTAGTGTAACTTTTACAGCTCAAGCATTTAAAGATTATCAATATTGGCAACAACACAATCAAAATTATTT
TAAAAAAGTGAATGCTTTACTTAAAAGTATTGCAAGAGATGGTTGTGTCGATGGTATTGGAAAACCAGAAGCATTAAAAG
GAAACTACGAAGGCTATTTCAGTAGAAGAGTTTCAATAGAACACCGATTAATATACAAAATTAAGGATGATTCAATATTC
GTAGTGTCTTGCAGATTTCATTATCAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9737.79 Da        Isoelectric Point: 4.1359

>AT31037 WP_002436168.1 NZ_AP014956:c278548-278291 [Staphylococcus capitis]
MPSVNYSNARQNFKELITKVNEDSVAYTITTKENENAVILAEKDYNAMLETMYLQSNLANVSHLNQSIMELNHNQTITIE
IDDNE

Download         Length: 258 bp

>AT31037 NZ_AP014956:c278548-278291 [Staphylococcus capitis]
ATGCCTTCAGTTAATTATTCAAACGCTAGACAGAATTTCAAAGAACTTATTACTAAAGTGAACGAGGATAGTGTGGCTTA
CACTATTACGACAAAGGAAAATGAAAATGCAGTGATTTTAGCTGAAAAGGATTATAATGCGATGTTGGAAACGATGTACC
TTCAATCCAATCTCGCTAATGTGTCTCACTTAAATCAATCAATTATGGAATTGAATCATAACCAAACAATTACAATAGAG
ATTGATGATAATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A507SVT5

Antitoxin

Source ID Structure
AlphaFold DB A0A1J4EAU6

References