31025

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2462193..2462377 Replicon chromosome
Accession NZ_AP014942
Organism Staphylococcus aureus strain FDA209P

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAFDA_RS12535 Protein ID WP_000482647.1
Coordinates 2462270..2462377 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2462193..2462253 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAFDA_RS12510 2457647..2457814 - 168 WP_001790576.1 hypothetical protein -
SAFDA_RS12520 2458045..2459778 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAFDA_RS12525 2459803..2461566 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2462193..2462253 + 61 - - Antitoxin
SAFDA_RS12535 2462270..2462377 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SAFDA_RS12540 2462511..2462897 - 387 WP_000779360.1 flippase GtxA -
SAFDA_RS12545 2463155..2464297 + 1143 WP_042727740.1 glycerate kinase -
SAFDA_RS12550 2464357..2465016 + 660 WP_000831298.1 membrane protein -
SAFDA_RS12555 2465198..2466409 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAFDA_RS12560 2466532..2467005 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T31025 WP_000482647.1 NZ_AP014942:c2462377-2462270 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T31025 NZ_AP014942:c2462377-2462270 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT31025 NZ_AP014942:2462193-2462253 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACTAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References