31009

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2201883..2202146 Replicon chromosome
Accession NZ_AP014921
Organism Staphylococcus aureus strain JH4899

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag JSA_RS11420 Protein ID WP_001802298.1
Coordinates 2202042..2202146 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2201883..2202047 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JSA_RS11400 2198132..2198797 - 666 WP_001024094.1 SDR family oxidoreductase -
JSA_RS11405 2198949..2199269 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
JSA_RS11410 2199271..2200251 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
JSA_RS11415 2200517..2201608 + 1092 WP_000495671.1 lytic regulatory protein -
- 2201883..2202047 + 165 - - Antitoxin
JSA_RS11420 2202042..2202146 - 105 WP_001802298.1 hypothetical protein Toxin
JSA_RS14855 2202307..2202790 - 484 Protein_2111 recombinase family protein -
JSA_RS11430 2202833..2203969 - 1137 WP_000115563.1 SAP domain-containing protein -
JSA_RS11435 2204258..2204350 + 93 WP_001790138.1 hypothetical protein -
JSA_RS11440 2205055..2205912 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
JSA_RS11445 2205980..2206762 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31009 WP_001802298.1 NZ_AP014921:c2202146-2202042 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31009 NZ_AP014921:c2202146-2202042 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT31009 NZ_AP014921:2201883-2202047 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References