Detailed information of TA system TA031001

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1860027..1860209
• Replicon: chromosome
• Accession: NZ_AP014921
• Organism: Staphylococcus aureus strain JH4899

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JSA_RS14840
• Protein ID: WP_001801861.1
• Coordinates: 1860027..1860122 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1860150..1860209 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JSA_RS09275	1855687..1856313	+	627	WP_000669046.1	hypothetical protein	-
JSA_RS09280	1856354..1856698	+	345	WP_000627551.1	DUF3969 family protein	-
JSA_RS09285	1856796..1857347	+	552	WP_096391891.1	hypothetical protein	-
JSA_RS09290	1857565..1858206	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
JSA_RS09295	1858320..1858505	-	186	WP_000809857.1	hypothetical protein	-
JSA_RS09300	1858507..1858683	-	177	WP_000375476.1	hypothetical protein	-
JSA_RS09305	1858694..1859077	-	384	WP_000070811.1	hypothetical protein	-
JSA_RS09315	1859681..1859824	-	144	WP_001549059.1	transposase	-
JSA_RS14840	1860027..1860122	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1860150..1860209	-	60	-	-	Antitoxin
JSA_RS09320	1860245..1860346	+	102	WP_001791893.1	hypothetical protein	-
JSA_RS09325	1860324..1860500	-	177	Protein_1758	transposase	-
JSA_RS09330	1860694..1861071	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1853127..1876981	23854

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T31001 WP_001801861.1 NZ_AP014921:1860027-1860122 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T31001 NZ_AP014921:1860027-1860122 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT31001 NZ_AP014921:c1860209-1860150 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin