Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 16923..17181 Replicon chromosome
Accession NZ_AP014856
Organism Escherichia albertii strain CB9786

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag AST72_RS00080 Protein ID WP_000809168.1
Coordinates 16923..17075 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokA
Locus tag -
Coordinates 17124..17181 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AST72_RS00065 12335..14251 + 1917 WP_000516135.1 molecular chaperone DnaK -
AST72_RS00070 14340..15470 + 1131 WP_001118445.1 molecular chaperone DnaJ -
AST72_RS00075 15733..16845 - 1113 WP_095575465.1 IS4 family transposase -
AST72_RS00080 16923..17075 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 17124..17181 + 58 - - Antitoxin
AST72_RS00090 17696..18457 + 762 WP_095575466.1 hypothetical protein -
AST72_RS00095 18478..19971 + 1494 WP_059227924.1 sulfatase-like hydrolase/transferase -
AST72_RS00100 20125..21372 + 1248 WP_059275868.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T30933 WP_000809168.1 NZ_AP014856:c17075-16923 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T30933 NZ_AP014856:c17075-16923 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT30933 NZ_AP014856:17124-17181 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References