Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2706442..2706686 Replicon chromosome
Accession NZ_AP014855
Organism Escherichia albertii strain NIAH_Bird_3

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag AST93_RS13365 Protein ID WP_000956458.1
Coordinates 2706442..2706594 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 2706639..2706686 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AST93_RS13355 2702227..2704884 - 2658 WP_059221338.1 CRISPR-associated helicase/endonuclease Cas3 -
AST93_RS13360 2705137..2706249 + 1113 WP_095574181.1 IS4 family transposase -
AST93_RS13365 2706442..2706594 - 153 WP_000956458.1 type I toxin-antitoxin system Hok family toxin Toxin
- 2706639..2706686 + 48 - - Antitoxin
AST93_RS13375 2706858..2707592 - 735 WP_001125132.1 phosphoadenosine phosphosulfate reductase -
AST93_RS13380 2707772..2709484 - 1713 WP_059221001.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
AST93_RS13385 2709484..2711283 - 1800 WP_095574182.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T30924 WP_000956458.1 NZ_AP014855:c2706594-2706442 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T30924 NZ_AP014855:c2706594-2706442 [Escherichia albertii]
ATGCTGACAAAATATGCCCTTGTGGCAATCATCGTACTGTGTTGTACAGTACTGGGATTCACGCTGATGGTAGGCGACTC
GCTGTGTGAGTTGAGTATCAGAGAACGTGGTATGGAGTTTAAGGCAGTTCTCGCTTACGAATCGAAGAAGTAG

Antitoxin


Download         Length: 48 bp

>AT30924 NZ_AP014855:2706639-2706686 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References