Detailed information of TA system TA030898

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 1967019..1967521
• Replicon: chromosome
• Accession: NZ_AP014836
• Organism: Candidatus Nitrosoglobus terrae strain TAO100

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: TAO_RS09260
• Protein ID: WP_096527636.1
• Coordinates: 1967019..1967282 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: TAO_RS09265
• Protein ID: WP_096527637.1
• Coordinates: 1967279..1967521 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TAO_RS09225	1962709..1962999	-	291	WP_096527632.1	co-chaperone GroES	-
TAO_RS09230	1963234..1963698	-	465	WP_096527821.1	FxsA family protein	-
TAO_RS09240	1964278..1964586	+	309	WP_145955159.1	hypothetical protein	-
TAO_RS09255	1965393..1967000	-	1608	WP_096527635.1	type I restriction-modification system subunit M	-
TAO_RS09260	1967019..1967282	-	264	WP_096527636.1	Txe/YoeB family addiction module toxin	Toxin
TAO_RS09265	1967279..1967521	-	243	WP_096527637.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
TAO_RS09270	1967623..1968909	-	1287	WP_096527638.1	restriction endonuclease subunit S	-
TAO_RS09275	1968899..1971868	-	2970	WP_096527639.1	type I restriction endonuclease subunit R	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (7-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10094.97 Da
• Isoelectric Point: 10.3577

>T30898 WP_096527636.1 NZ_AP014836:c1967282-1967019 [Candidatus Nitrosoglobus terrae]
VIWRLVYSKQAQKDAKKLIARGLRAKAQELLALILEDPYKKPPSFEKLVGDLAGICSRRINIQHRLVYQVLEDGPVVKIL
RLWSHYE

Nucleotide

• Length: 264 bp

>T30898 NZ_AP014836:c1967282-1967019 [Candidatus Nitrosoglobus terrae]
GTGATATGGCGGCTAGTTTATAGTAAGCAGGCTCAGAAAGATGCAAAAAAGCTGATTGCAAGGGGCTTGCGCGCAAAGGC
TCAGGAGCTGCTAGCATTAATCTTAGAAGATCCCTATAAAAAACCGCCTTCGTTTGAGAAACTGGTTGGCGACTTGGCGG
GCATCTGTTCCCGTCGAATTAATATTCAGCACCGCTTGGTTTATCAGGTGTTGGAAGATGGGCCTGTAGTCAAAATTCTA
CGGCTGTGGAGTCACTACGAATGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8863.03 Da
• Isoelectric Point: 4.0075

>AT30898 WP_096527637.1 NZ_AP014836:c1967521-1967279 [Candidatus Nitrosoglobus terrae]
MNGITVTEARSNLYRLIDEAAESHQPIVIMGKRNKAVLVSEEDWAAIQETLFLLSVPGMGESIREGMATPIDECDEDLGW

Nucleotide

• Length: 243 bp

>AT30898 NZ_AP014836:c1967521-1967279 [Candidatus Nitrosoglobus terrae]
ATGAACGGAATTACGGTAACTGAGGCTCGTAGCAATCTATATCGGTTGATTGATGAAGCCGCTGAGTCTCATCAGCCCAT
CGTGATTATGGGCAAGCGAAACAAGGCTGTTTTGGTATCTGAAGAAGATTGGGCTGCCATCCAAGAAACTTTGTTCCTGC
TTTCTGTGCCGGGTATGGGAGAGTCGATTCGTGAGGGTATGGCTACCCCAATTGATGAATGCGATGAGGATCTCGGTTGG
TGA