30873

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 944006..944598 Replicon chromosome
Accession NZ_AP014703
Organism Pseudomonas sp. St290

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag PBDP_RS03970 Protein ID WP_212801849.1
Coordinates 944320..944598 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag PBDP_RS03965 Protein ID WP_212801848.1
Coordinates 944006..944311 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBDP_RS03945 (PBDP_0777) 939261..940148 - 888 WP_212801845.1 proline iminopeptidase-family hydrolase -
PBDP_RS03950 (PBDP_0778) 940313..941074 + 762 WP_135843586.1 LuxR family transcriptional regulator -
PBDP_RS03955 (PBDP_0779) 941165..942064 + 900 WP_212801846.1 proline iminopeptidase-family hydrolase -
PBDP_RS03960 (PBDP_0780) 942444..943925 + 1482 WP_212801847.1 leucine-rich repeat domain-containing protein -
PBDP_RS03965 (PBDP_0781) 944006..944311 - 306 WP_212801848.1 HigA family addiction module antitoxin Antitoxin
PBDP_RS03970 (PBDP_0782) 944320..944598 - 279 WP_212801849.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PBDP_RS03975 (PBDP_0783) 944877..945905 - 1029 WP_249411836.1 GlxA family transcriptional regulator -
PBDP_RS03980 (PBDP_0784) 946064..946933 + 870 WP_109753440.1 ABC transporter substrate-binding protein -
PBDP_RS03985 (PBDP_0785) 947012..947800 + 789 WP_109753441.1 amino acid ABC transporter ATP-binding protein -
PBDP_RS03990 (PBDP_0786) 947800..948456 + 657 WP_212801851.1 amino acid ABC transporter permease -
PBDP_RS03995 (PBDP_0787) 948453..949136 + 684 WP_109753443.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-83)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10526.90 Da        Isoelectric Point: 7.2441

>T30873 WP_212801849.1 NZ_AP014703:c944598-944320 [Pseudomonas sp. St290]
MIRSFRCADTQTLFETGKTRRWAAILSVAERKLSMLDAAVDLNDLRSPPGNRLEQLHGDREGQHSIRINGQYRICFIWGA
NGPENVEIVDYH

Download         Length: 279 bp

>T30873 NZ_AP014703:c944598-944320 [Pseudomonas sp. St290]
ATGATCAGAAGCTTCAGATGCGCCGACACCCAAACTCTTTTTGAAACCGGCAAAACCCGGCGCTGGGCCGCCATCCTTTC
AGTGGCGGAACGAAAGCTGAGCATGCTCGATGCGGCGGTCGATCTCAACGACCTACGCTCCCCACCTGGAAACCGGCTGG
AGCAGTTGCATGGCGACAGGGAAGGCCAACACAGCATCCGGATTAACGGTCAGTACCGGATCTGTTTTATCTGGGGCGCC
AACGGCCCCGAAAATGTAGAAATCGTAGATTATCACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11171.95 Da        Isoelectric Point: 6.7173

>AT30873 WP_212801848.1 NZ_AP014703:c944311-944006 [Pseudomonas sp. St290]
MFKNGMRPVHPGEILKEEYLEPLGLTAAALARALHVSAPTVNDIVLMRRSVSADVALRLAAALETSAQFWLNLQTAYDLR
TAEIAKGEQIYREVEKIPHCA

Download         Length: 306 bp

>AT30873 NZ_AP014703:c944311-944006 [Pseudomonas sp. St290]
ATGTTTAAGAATGGCATGAGGCCCGTACACCCTGGAGAAATTCTCAAGGAAGAGTATCTGGAACCGCTTGGCCTTACGGC
CGCTGCGCTCGCGAGGGCTTTGCACGTGTCTGCCCCGACAGTAAACGACATCGTATTGATGCGTCGTAGCGTTAGTGCAG
ATGTGGCTTTGCGCCTGGCAGCTGCATTGGAAACGTCGGCGCAGTTTTGGCTGAATTTGCAGACTGCGTATGATTTACGT
ACCGCTGAGATTGCAAAAGGGGAGCAGATTTACAGGGAAGTCGAGAAGATTCCTCACTGCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References