Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1832499..1832679 Replicon chromosome
Accession NZ_AP014653
Organism Staphylococcus aureus strain TMUS2134

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAJPND4_RS14765 Protein ID WP_001801861.1
Coordinates 1832499..1832594 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1832622..1832679 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAJPND4_RS08885 1827541..1828167 + 627 WP_000669021.1 hypothetical protein -
SAJPND4_RS08890 1828208..1828549 + 342 WP_000627547.1 DUF3969 family protein -
SAJPND4_RS08895 1828650..1829221 + 572 Protein_1705 hypothetical protein -
SAJPND4_RS08900 1829419..1829976 - 558 WP_000864139.1 ImmA/IrrE family metallo-endopeptidase -
SAJPND4_RS08910 1830347..1830523 - 177 WP_000375476.1 hypothetical protein -
SAJPND4_RS08915 1830534..1830917 - 384 WP_000070811.1 hypothetical protein -
SAJPND4_RS08920 1831602..1832048 - 447 WP_000747802.1 DUF1433 domain-containing protein -
SAJPND4_RS14765 1832499..1832594 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1832622..1832679 - 58 - - Antitoxin
SAJPND4_RS08930 1832717..1832818 + 102 WP_001791232.1 hypothetical protein -
SAJPND4_RS14395 1832796..1832978 - 183 Protein_1712 transposase -
SAJPND4_RS08935 1833166..1833540 - 375 WP_000695818.1 DUF1433 domain-containing protein -
SAJPND4_RS08940 1833562..1833909 - 348 WP_001566695.1 DUF1433 domain-containing protein -
SAJPND4_RS08945 1834146..1834562 - 417 WP_020978241.1 DUF1433 domain-containing protein -
SAJPND4_RS08950 1835209..1836327 - 1119 WP_000072558.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA / selk 1824983..1862494 37511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T30855 WP_001801861.1 NZ_AP014653:1832499-1832594 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T30855 NZ_AP014653:1832499-1832594 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT30855 NZ_AP014653:c1832679-1832622 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References