30801

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1582293..1582926 Replicon chromosome
Accession NZ_AP014635
Organism Vibrio tritonius strain AM2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag JCM16456_RS07120 Protein ID WP_068715947.1
Coordinates 1582293..1582625 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag JCM16456_RS07125 Protein ID WP_068713556.1
Coordinates 1582612..1582926 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCM16456_RS07095 1577960..1578340 + 381 WP_068713552.1 hypothetical protein -
JCM16456_RS07100 1578454..1579230 - 777 WP_068713553.1 ferredoxin--NADP reductase -
JCM16456_RS07105 1579292..1579843 - 552 WP_068713554.1 class I SAM-dependent methyltransferase -
JCM16456_RS07110 1580347..1581876 + 1530 WP_082712239.1 DUF1593 domain-containing protein -
JCM16456_RS07120 1582293..1582625 + 333 WP_068715947.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JCM16456_RS07125 1582612..1582926 + 315 WP_068713556.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JCM16456_RS07130 1583041..1583343 - 303 WP_068713557.1 type II toxin-antitoxin system RelE/ParE family toxin -
JCM16456_RS07135 1583361..1583603 - 243 WP_068713558.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
JCM16456_RS07140 1583818..1584216 + 399 WP_068713559.1 hypothetical protein -
JCM16456_RS07145 1584295..1584684 + 390 WP_068713560.1 hypothetical protein -
JCM16456_RS07150 1584737..1585939 - 1203 WP_068713561.1 MFS transporter -
JCM16456_RS07155 1586281..1587297 - 1017 WP_068713562.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(13-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-92)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 13013.78 Da        Isoelectric Point: 9.6344

>T30801 WP_068715947.1 NZ_AP014635:1582293-1582625 [Vibrio tritonius]
MKSVFVESSIFEKYREHYLNDDEYRLFQAELMSNPKYGDVIQGTGGLRKIRVASKGKGKRGGSRVIYYYLDEHHRFYLLT
IYAKNEMSDLTADQKKQLKAFMEAWRNEQS

Download         Length: 333 bp

>T30801 NZ_AP014635:1582293-1582625 [Vibrio tritonius]
ATGAAAAGTGTATTTGTTGAATCGAGTATATTTGAAAAGTACCGAGAGCATTATCTTAACGATGACGAGTATAGGCTTTT
TCAAGCGGAACTCATGTCTAATCCCAAGTATGGCGATGTAATCCAAGGTACAGGAGGTTTGCGAAAAATTCGAGTAGCAA
GCAAGGGCAAAGGGAAGCGTGGTGGTTCACGCGTTATCTATTACTATCTCGATGAACATCATCGATTCTACTTGCTTACC
ATTTATGCAAAGAATGAAATGTCGGATTTAACCGCAGATCAAAAGAAACAGTTAAAAGCTTTTATGGAGGCATGGCGCAA
TGAGCAATCGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11879.32 Da        Isoelectric Point: 5.9765

>AT30801 WP_068713556.1 NZ_AP014635:1582612-1582926 [Vibrio tritonius]
MSNRDLFTELSSALIEAKEHSEGKLTLKNHQFNNVGELDISPDEIVDIREQFNMSRGVFARLLHTSSRTLENWEQGRSTP
NGQAITLLRLVQRHPETLTHIAEL

Download         Length: 315 bp

>AT30801 NZ_AP014635:1582612-1582926 [Vibrio tritonius]
ATGAGCAATCGTGATCTATTTACAGAATTAAGTTCAGCTCTTATTGAAGCTAAAGAGCATTCAGAAGGTAAGTTAACGCT
GAAAAATCATCAGTTTAATAATGTTGGTGAATTAGACATTTCACCTGATGAGATAGTTGATATCCGTGAACAATTTAATA
TGTCACGAGGGGTATTTGCCCGTTTACTTCATACGTCGTCACGTACATTGGAAAACTGGGAACAAGGGCGCAGTACTCCC
AATGGGCAAGCAATAACACTTCTAAGATTGGTTCAACGCCACCCTGAAACTCTGACTCATATCGCAGAGCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References