Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 4413637..4414291 | Replicon | chromosome |
Accession | NZ_AP014628 | ||
Organism | Pseudomonas sp. St29 |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A0D6BLD7 |
Locus tag | PST29_RS19545 | Protein ID | WP_060840140.1 |
Coordinates | 4413637..4413987 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A0D6BLA0 |
Locus tag | PST29_RS19550 | Protein ID | WP_060840141.1 |
Coordinates | 4413974..4414291 (+) | Length | 106 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PST29_RS19535 | 4410396..4411928 | + | 1533 | WP_016965722.1 | NADH-quinone oxidoreductase subunit M | - |
PST29_RS19540 | 4411936..4413399 | + | 1464 | WP_015636299.1 | NADH-quinone oxidoreductase subunit NuoN | - |
PST29_RS19545 | 4413637..4413987 | + | 351 | WP_060840140.1 | hypothetical protein | Toxin |
PST29_RS19550 | 4413974..4414291 | + | 318 | WP_060840141.1 | XRE family transcriptional regulator | Antitoxin |
PST29_RS19555 | 4414364..4415746 | - | 1383 | WP_060844109.1 | cysteine--tRNA ligase | - |
PST29_RS19560 | 4415765..4417465 | - | 1701 | WP_060844110.1 | glutamine--tRNA ligase/YqeY domain fusion protein | - |
PST29_RS19565 | 4417736..4418239 | + | 504 | WP_060840144.1 | peptidyl-prolyl cis-trans isomerase | - |
PST29_RS19570 | 4418236..4418988 | + | 753 | WP_060840145.1 | UDP-2,3-diacylglucosamine diphosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 14022.12 Da Isoelectric Point: 8.9935
>T30795 WP_060840140.1 NZ_AP014628:4413637-4413987 [Pseudomonas sp. St29]
MNALFIELPAFARYRRDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT
MNALFIELPAFARYRRDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT
Download Length: 351 bp
>T30795 NZ_AP014628:4413637-4413987 [Pseudomonas sp. St29]
ATGAATGCTCTGTTTATTGAACTGCCGGCATTTGCACGATACCGAAGGGACTTCCTTGACGACGAGTTGTTCTGCGAACT
GCAGATCGAGTTGCTGCGCCACCCGCACGCGGGAGTGCTGATTCAGGGCACTGGCGGCTTGCGCAAGATGCGTTTCATCG
ATGAGCGACGCAACAAGGGCAGGCGTGGCGGGCTGAGGGTGATCTATTACTGGTGGTCCGGAGGGGCGCAGTTCTGGCTC
TTCACCCTGTTCGATAAGGAGCAGATGGACGACCTGCTACCGCAGCAGCGACAACAGCTCAAACAACTGCTGGAACGTGA
AATCGAGGCCAGAAGACATGACCAAACGTGA
ATGAATGCTCTGTTTATTGAACTGCCGGCATTTGCACGATACCGAAGGGACTTCCTTGACGACGAGTTGTTCTGCGAACT
GCAGATCGAGTTGCTGCGCCACCCGCACGCGGGAGTGCTGATTCAGGGCACTGGCGGCTTGCGCAAGATGCGTTTCATCG
ATGAGCGACGCAACAAGGGCAGGCGTGGCGGGCTGAGGGTGATCTATTACTGGTGGTCCGGAGGGGCGCAGTTCTGGCTC
TTCACCCTGTTCGATAAGGAGCAGATGGACGACCTGCTACCGCAGCAGCGACAACAGCTCAAACAACTGCTGGAACGTGA
AATCGAGGCCAGAAGACATGACCAAACGTGA
Antitoxin
Download Length: 106 a.a. Molecular weight: 12067.91 Da Isoelectric Point: 10.7043
>AT30795 WP_060840141.1 NZ_AP014628:4413974-4414291 [Pseudomonas sp. St29]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITATEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLIRLVQRYPDTVERLASLA
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITATEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLIRLVQRYPDTVERLASLA
Download Length: 318 bp
>AT30795 NZ_AP014628:4413974-4414291 [Pseudomonas sp. St29]
ATGACCAAACGTGACATCTTTTCCGAACTGGTAGAAGGCATCGACGCCCTCACCCAGGAGCGCCAGGGCAAGATCACCCT
GCGCAGCCATAAAGTGAAGCTGGACAAGCTGCCCCCCATCACTGCCACCGAGGTGATGAACATCCGCCAGCAACTCAATC
TCTCGCGCTCGGTATTCGCCATGTACCTGCGCACCAACACCCGCACCCTGGAGAACTGGGAACAGGGCCGTGCCACACCC
AATGCCCAGGCCACCACCCTGATCCGCCTGGTGCAACGCTACCCCGATACCGTGGAGCGCCTAGCCTCGCTGGCCTGA
ATGACCAAACGTGACATCTTTTCCGAACTGGTAGAAGGCATCGACGCCCTCACCCAGGAGCGCCAGGGCAAGATCACCCT
GCGCAGCCATAAAGTGAAGCTGGACAAGCTGCCCCCCATCACTGCCACCGAGGTGATGAACATCCGCCAGCAACTCAATC
TCTCGCGCTCGGTATTCGCCATGTACCTGCGCACCAACACCCGCACCCTGGAGAACTGGGAACAGGGCCGTGCCACACCC
AATGCCCAGGCCACCACCCTGATCCGCCTGGTGCAACGCTACCCCGATACCGTGGAGCGCCTAGCCTCGCTGGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0D6BLD7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0D6BLA0 |