Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4301577..4302231 Replicon chromosome
Accession NZ_AP014623
Organism Pseudomonas chlororaphis subsp. aurantiaca strain StFRB508

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PCAU_RS19375 Protein ID WP_096376050.1
Coordinates 4301577..4301927 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PCAU_RS19380 Protein ID WP_025804712.1
Coordinates 4301917..4302231 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCAU_RS19365 4298326..4299858 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
PCAU_RS19370 4299866..4301329 + 1464 WP_009044594.1 NADH-quinone oxidoreductase subunit NuoN -
PCAU_RS19375 4301577..4301927 + 351 WP_096376050.1 toxin Toxin
PCAU_RS19380 4301917..4302231 + 315 WP_025804712.1 transcriptional regulator Antitoxin
PCAU_RS19385 4302412..4304154 - 1743 WP_096374831.1 ABC transporter substrate-binding protein -
PCAU_RS19390 4304205..4304477 - 273 WP_096374832.1 DUF2160 domain-containing protein -
PCAU_RS19395 4304488..4305288 - 801 WP_038577819.1 carbohydrate ABC transporter permease -
PCAU_RS19400 4305300..4306166 - 867 WP_038577816.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13803.77 Da        Isoelectric Point: 9.4187

>T30778 WP_096376050.1 NZ_AP014623:4301577-4301927 [Pseudomonas chlororaphis subsp. aurantiaca]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T30778 NZ_AP014623:4301577-4301927 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGGACGCACTTTTCATTGAGTTACCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAATTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACCGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11891.81 Da        Isoelectric Point: 10.7886

>AT30778 WP_025804712.1 NZ_AP014623:4301917-4302231 [Pseudomonas chlororaphis subsp. aurantiaca]
MKRDIFSELVEGFDALAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT30778 NZ_AP014623:4301917-4302231 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCCACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCCGAAGAAGTGCTGGCCGTGCGCGAGCAGCTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGAACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACCACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCACTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References