Detailed information of TA system TA030687

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 639398..640104
• Replicon: chromosome
• Accession: NZ_AP014569
• Organism: Serpentinomonas mccroryi strain B1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: A0A060NNA1
• Locus tag: SMCB_RS02965
• Protein ID: WP_045534957.1
• Coordinates: 639802..640104 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: SMCB_RS02960
• Protein ID: WP_045534955.1
• Coordinates: 639398..639799 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SMCB_RS02925	635143..636252	+	1110	WP_045534946.1	YeeE/YedE family protein	-
SMCB_RS02930	636245..637078	+	834	WP_045534948.1	tRNA threonylcarbamoyladenosine dehydratase	-
SMCB_RS02940	637519..637803	-	285	WP_045534950.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	-
SMCB_RS02945	637800..638081	-	282	WP_045534952.1	hypothetical protein	-
SMCB_RS02950	638443..638847	-	405	WP_045534954.1	type II toxin-antitoxin system VapC family toxin	-
SMCB_RS02955	638857..639108	-	252	WP_045537499.1	AbrB family transcriptional regulator	-
SMCB_RS02960	639398..639799	-	402	WP_045534955.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
SMCB_RS02965	639802..640104	-	303	WP_045534957.1	type II toxin-antitoxin system MqsR family toxin	Toxin
SMCB_RS02970	640442..640654	-	213	WP_045537501.1	type II toxin-antitoxin system HicB family antitoxin	-
SMCB_RS02975	641055..641837	-	783	WP_197539310.1	hypothetical protein	-
SMCB_RS02980	641856..642407	-	552	WP_197539311.1	DUF4433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-99)

Antitoxin

• Zinc finger, MqsA-type (3-47)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 10812.51 Da
• Isoelectric Point: 6.2076

>T30687 WP_045534957.1 NZ_AP014569:c640104-639802 [Serpentinomonas mccroryi]
MEKGTPHCKLPVVKALVEAGQVRATASAFSGARDLGIDDLDGMCAVVLALTGADFYKSMTTHADHRVWQDVYRGKTPCGD
EVYLKLTVIDGVLIVSFKEL

Nucleotide

• Length: 303 bp

>T30687 NZ_AP014569:c640104-639802 [Serpentinomonas mccroryi]
ATGGAAAAAGGCACCCCGCACTGCAAGCTTCCAGTCGTCAAAGCCTTGGTAGAGGCGGGTCAGGTCAGGGCCACGGCCAG
CGCCTTCAGTGGGGCGCGTGATCTGGGCATTGATGACCTAGACGGGATGTGCGCTGTAGTCTTGGCGCTCACTGGCGCCG
ACTTCTACAAGAGCATGACCACCCATGCCGATCATCGTGTTTGGCAAGACGTGTACCGAGGCAAGACGCCATGCGGCGAT
GAGGTGTATCTGAAGCTGACCGTCATCGATGGTGTGTTGATCGTTTCCTTCAAGGAGCTATGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14830.03 Da
• Isoelectric Point: 7.6647

>AT30687 WP_045534955.1 NZ_AP014569:c639799-639398 [Serpentinomonas mccroryi]
MKCPCCGAAELIHDTRDMSYTYKGEHTIIPAVTGDFCPACGEVVLNREHGDRYSEMVGLFQRQVNAAYVDPSYIAKVRKK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLLKLLDRHPDLLSEVRAT

Nucleotide

• Length: 402 bp

>AT30687 NZ_AP014569:c639799-639398 [Serpentinomonas mccroryi]
ATGAAATGCCCCTGCTGCGGCGCGGCGGAACTGATCCATGACACGCGCGATATGTCCTACACCTACAAGGGCGAACACAC
CATCATCCCAGCGGTGACGGGCGATTTTTGCCCTGCTTGCGGTGAAGTGGTCTTGAACCGTGAGCATGGCGACCGCTACA
GCGAAATGGTCGGCCTGTTTCAACGCCAGGTCAATGCCGCCTATGTCGATCCGAGCTACATCGCCAAGGTGCGAAAGAAG
CTCGATCTTGACCAACGGCAGGCGGCTGAGCTCTTTGGTGGCGGCGTCAACGCCTTTTCGCGCTACGAGAACGGCAAGAC
CAAGCCGCCGCTGTCCTTGGTCAAGCTGCTCAAACTGCTGGACCGCCACCCCGATCTGCTCTCAGAGGTCAGAGCCACCT
GA

Structures

Toxin

• AlphaFold DB: A0A060NNA1