Detailed information of TA system TA030681

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 2409692..2410360
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: SRAA_RS11200
• Protein ID: WP_045532785.1
• Coordinates: 2410010..2410360 (-)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: SRAA_RS12360
• Protein ID: WP_045532783.1
• Coordinates: 2409692..2410006 (-)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRAA_RS12360	2409692..2410006	-	315	WP_045532783.1	transcriptional regulator	Antitoxin
SRAA_RS11200	2410010..2410360	-	351	WP_045532785.1	hypothetical protein	Toxin
SRAA_RS11205	2410532..2412370	-	1839	WP_045532787.1	patatin-like phospholipase family protein	-
SRAA_RS11210	2412407..2413594	-	1188	WP_045532789.1	tRNA 2-thiouridine(34) synthase MnmA	-
SRAA_RS11215	2413623..2414912	-	1290	WP_045532791.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (43-88)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13498.45 Da
• Isoelectric Point: 9.7093

>T30681 WP_045532785.1 NZ_AP014568:c2410360-2410010 [Serpentinomonas raichei]
VHALFIELPPFERQRANYLDDEGYRALQLDLMRNPLAGDVIKGTGGLRKLRQPDPLRGKGKRGGLRVIYYWWLGGSQFWL
FTLYDKDQADDLTAEQRSAIKKLLDAERQHRQPKEC

Nucleotide

• Length: 351 bp

>T30681 NZ_AP014568:c2410360-2410010 [Serpentinomonas raichei]
GTGCATGCTTTGTTTATCGAGCTCCCGCCGTTCGAGCGGCAGCGCGCCAACTACCTTGACGATGAAGGCTATCGGGCTTT
GCAGCTGGATTTGATGCGCAACCCTCTGGCCGGTGATGTGATTAAAGGCACGGGGGGTCTGCGCAAGCTTCGTCAACCAG
ACCCTCTACGCGGCAAAGGCAAGCGTGGCGGGTTGCGTGTGATTTATTACTGGTGGCTTGGGGGTAGCCAGTTCTGGCTG
TTCACCCTCTACGACAAAGACCAAGCCGATGATCTGACGGCCGAACAACGCAGTGCCATCAAGAAACTGCTGGATGCCGA
ACGCCAACACCGTCAACCCAAGGAGTGCTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 12109.12 Da
• Isoelectric Point: 10.7911

>AT30681 WP_045532783.1 NZ_AP014568:c2410006-2409692 [Serpentinomonas raichei]
MKKRDVFAELLEGFDALKSEREGKLTLRQIKVQDKPVPTLAPQELIQVREKLHLSRALFARYLRTNPRTLENWEQGRAKP
NAQAVLLIRMVSQFPDTVQRLETV

Nucleotide

• Length: 315 bp

>AT30681 NZ_AP014568:c2410006-2409692 [Serpentinomonas raichei]
ATGAAAAAACGTGATGTTTTTGCTGAATTGCTGGAAGGCTTTGACGCCCTGAAGTCTGAACGTGAAGGCAAGCTGACTTT
ACGGCAAATCAAGGTACAGGACAAACCCGTTCCCACATTGGCGCCTCAGGAATTGATCCAAGTGCGCGAGAAACTTCACC
TCTCGCGAGCCTTATTTGCACGCTACTTACGCACCAACCCGCGAACCTTGGAGAACTGGGAGCAGGGTCGAGCAAAGCCG
AACGCTCAAGCGGTGCTGCTGATTCGGATGGTTTCGCAATTCCCAGATACGGTGCAACGCTTGGAAACGGTTTGA