Detailed information of TA system TA030679

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 2362532..2363232
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: A0A060NIR8
• Locus tag: SRAA_RS11030
• Protein ID: WP_045532738.1
• Coordinates: 2362936..2363232 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: SRAA_RS11025
• Protein ID: WP_045532736.1
• Coordinates: 2362532..2362933 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRAA_RS11010	2358937..2360169	+	1233	WP_045530664.1	IS110 family transposase	-
SRAA_RS11015	2360269..2361636	-	1368	WP_045532734.1	glutamine synthetase family protein	-
SRAA_RS11020	2361633..2362415	-	783	WP_052467567.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
SRAA_RS11025	2362532..2362933	-	402	WP_045532736.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
SRAA_RS11030	2362936..2363232	-	297	WP_045532738.1	type II toxin-antitoxin system MqsR family toxin	Toxin
SRAA_RS11035	2363293..2364612	-	1320	WP_197538510.1	FAD-binding oxidoreductase	-
SRAA_RS11040	2364620..2365576	-	957	WP_045532739.1	agmatinase	-
SRAA_RS11045	2365653..2366903	-	1251	WP_045532741.1	YbfB/YjiJ family MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2358937..2360169	1232

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (6-97)

Antitoxin

• Zinc finger, MqsA-type (3-46)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10678.35 Da
• Isoelectric Point: 7.4000

>T30679 WP_045532738.1 NZ_AP014568:c2363232-2362936 [Serpentinomonas raichei]
VEKRSPHSKLSVVKALVEAGKVRATHSARLGAAALGLDLSAVLAVVMELTPADFYKSMTTHADHTVWQDVYRPSTQTGDV
YLKLTVIDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T30679 NZ_AP014568:c2363232-2362936 [Serpentinomonas raichei]
GTGGAGAAACGAAGCCCACACAGCAAGCTGTCAGTCGTCAAAGCCTTGGTAGAGGCTGGCAAGGTGCGTGCGACCCATTC
AGCCAGGCTTGGGGCCGCTGCATTGGGGTTGGATCTCTCCGCCGTGTTGGCCGTGGTGATGGAGCTCACCCCTGCAGATT
TTTACAAGAGCATGACTACCCATGCCGACCACACGGTATGGCAGGACGTGTACCGCCCAAGCACGCAGACGGGCGATGTG
TACCTGAAACTGACGGTCATTGATGACGTGCTGATCGTGTCCTTTAAGGAGCTATGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14712.99 Da
• Isoelectric Point: 5.7671

>AT30679 WP_045532736.1 NZ_AP014568:c2362933-2362532 [Serpentinomonas raichei]
MKCPVCGAAELIHDTRDLPYTYKGEATTIPAVTADFCPACDESITDMPETERVMREMQAFNKQVNAAIVDPGFILNVRKK
LDLGQREAAEIFGGGINAFSRYETGKTKPPLALVKLFKLLDRHPDLLNEVKTA

Nucleotide

• Length: 402 bp

>AT30679 NZ_AP014568:c2362933-2362532 [Serpentinomonas raichei]
ATGAAATGCCCGGTTTGCGGCGCGGCGGAACTGATCCATGACACCCGCGACCTGCCCTATACCTACAAGGGTGAAGCCAC
CACCATCCCGGCGGTGACGGCCGATTTTTGCCCTGCCTGTGATGAGTCCATTACCGACATGCCAGAAACCGAGCGTGTCA
TGCGGGAGATGCAGGCGTTCAACAAGCAGGTGAACGCGGCCATTGTTGACCCCGGTTTCATCCTCAACGTGCGCAAGAAG
CTCGACCTCGGGCAGCGCGAAGCCGCCGAAATTTTTGGCGGTGGCATCAATGCCTTCTCGCGCTACGAGACCGGCAAGAC
CAAGCCACCACTGGCACTGGTCAAGCTGTTCAAGCTGTTGGATCGTCACCCCGATCTGCTGAACGAAGTGAAAACCGCCT
GA

Structures

Toxin

• AlphaFold DB: A0A060NIR8