Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
Location | 384776..385391 | Replicon | chromosome |
Accession | NZ_AP014568 | ||
Organism | Serpentinomonas raichei strain A1 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | SRAA_RS01840 | Protein ID | WP_197538516.1 |
Coordinates | 385059..385391 (-) | Length | 111 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | SRAA_RS01835 | Protein ID | WP_045530658.1 |
Coordinates | 384776..385066 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SRAA_RS01810 | 381476..381769 | - | 294 | WP_045530648.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
SRAA_RS01815 | 381766..381990 | - | 225 | WP_045530650.1 | addiction module protein | - |
SRAA_RS01820 | 382073..382762 | - | 690 | WP_045530652.1 | hypothetical protein | - |
SRAA_RS01825 | 382996..384087 | + | 1092 | WP_197538515.1 | NDP-sugar synthase | - |
SRAA_RS01830 | 384115..384714 | + | 600 | WP_045530656.1 | lysophospholipid acyltransferase family protein | - |
SRAA_RS01835 | 384776..385066 | - | 291 | WP_045530658.1 | helix-turn-helix domain-containing protein | Antitoxin |
SRAA_RS01840 | 385059..385391 | - | 333 | WP_197538516.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
SRAA_RS01845 | 385520..385744 | + | 225 | WP_082039846.1 | hypothetical protein | - |
SRAA_RS01850 | 385856..386176 | + | 321 | WP_045530660.1 | transcriptional regulator | - |
SRAA_RS12570 | 386321..386986 | - | 666 | WP_171820201.1 | hypothetical protein | - |
SRAA_RS01865 | 387831..389063 | + | 1233 | WP_045530664.1 | IS110 family transposase | - |
SRAA_RS01870 | 389274..389606 | - | 333 | WP_045533080.1 | HigA family addiction module antidote protein | - |
SRAA_RS12575 | 389621..389704 | - | 84 | WP_082040069.1 | hypothetical protein | - |
SRAA_RS01875 | 389920..390198 | - | 279 | WP_045530666.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 381766..390406 | 8640 | |
- | flank | IS/Tn | - | - | 387831..389063 | 1232 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 111 a.a. Molecular weight: 12374.43 Da Isoelectric Point: 6.9497
>T30663 WP_197538516.1 NZ_AP014568:c385391-385059 [Serpentinomonas raichei]
MEVMVFVELPIFIRCAAELFADEDIAALQNTLLENPAAGDLIPGGRGLRKLRVPLPGRGKRSGARVIYYHWVSKEQCYLI
YAYAKNVSTNLTPVQLRRLAEIMQAEIPDE
MEVMVFVELPIFIRCAAELFADEDIAALQNTLLENPAAGDLIPGGRGLRKLRVPLPGRGKRSGARVIYYHWVSKEQCYLI
YAYAKNVSTNLTPVQLRRLAEIMQAEIPDE
Download Length: 333 bp
>T30663 NZ_AP014568:c385391-385059 [Serpentinomonas raichei]
ATGGAAGTCATGGTTTTTGTGGAACTTCCGATCTTCATCCGCTGTGCAGCCGAACTGTTCGCGGATGAGGATATCGCCGC
GCTGCAGAACACCTTGCTGGAAAATCCCGCCGCTGGCGACTTGATTCCCGGCGGCAGGGGGCTGCGCAAGTTGCGTGTTC
CGTTGCCTGGCAGGGGCAAGCGCAGTGGGGCACGGGTCATCTACTACCACTGGGTGAGCAAGGAGCAGTGCTACTTGATC
TATGCCTATGCGAAAAATGTCAGCACCAATCTGACACCCGTTCAACTGCGGCGGTTGGCCGAGATCATGCAAGCGGAGAT
ACCAGATGAATGA
ATGGAAGTCATGGTTTTTGTGGAACTTCCGATCTTCATCCGCTGTGCAGCCGAACTGTTCGCGGATGAGGATATCGCCGC
GCTGCAGAACACCTTGCTGGAAAATCCCGCCGCTGGCGACTTGATTCCCGGCGGCAGGGGGCTGCGCAAGTTGCGTGTTC
CGTTGCCTGGCAGGGGCAAGCGCAGTGGGGCACGGGTCATCTACTACCACTGGGTGAGCAAGGAGCAGTGCTACTTGATC
TATGCCTATGCGAAAAATGTCAGCACCAATCTGACACCCGTTCAACTGCGGCGGTTGGCCGAGATCATGCAAGCGGAGAT
ACCAGATGAATGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10831.45 Da Isoelectric Point: 10.5808
>AT30663 WP_045530658.1 NZ_AP014568:c385066-384776 [Serpentinomonas raichei]
MNDQQFDELLDSVRDMGRHMRGEKLLGVRVQAFPEPDVKAIRERTGLSQSRFAHLIGVKPKTLQNWEQHRVRPAGPARAL
LKIVEANPDALSALHA
MNDQQFDELLDSVRDMGRHMRGEKLLGVRVQAFPEPDVKAIRERTGLSQSRFAHLIGVKPKTLQNWEQHRVRPAGPARAL
LKIVEANPDALSALHA
Download Length: 291 bp
>AT30663 NZ_AP014568:c385066-384776 [Serpentinomonas raichei]
ATGAATGACCAACAGTTCGACGAGTTGCTCGACAGCGTGCGCGACATGGGGCGCCATATGCGCGGCGAGAAGCTGCTGGG
CGTTCGCGTGCAGGCGTTTCCTGAGCCCGATGTCAAGGCGATCCGTGAGCGCACCGGTCTGTCGCAGAGTCGTTTCGCCC
ACCTGATCGGCGTCAAGCCCAAGACCCTGCAGAACTGGGAGCAACATCGCGTGCGTCCAGCAGGACCTGCGCGCGCCTTG
CTAAAGATCGTCGAAGCCAACCCTGATGCGCTCTCGGCGCTTCACGCATAG
ATGAATGACCAACAGTTCGACGAGTTGCTCGACAGCGTGCGCGACATGGGGCGCCATATGCGCGGCGAGAAGCTGCTGGG
CGTTCGCGTGCAGGCGTTTCCTGAGCCCGATGTCAAGGCGATCCGTGAGCGCACCGGTCTGTCGCAGAGTCGTTTCGCCC
ACCTGATCGGCGTCAAGCCCAAGACCCTGCAGAACTGGGAGCAACATCGCGTGCGTCCAGCAGGACCTGCGCGCGCCTTG
CTAAAGATCGTCGAAGCCAACCCTGATGCGCTCTCGGCGCTTCACGCATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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