Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 1229333..1229897 Replicon chromosome
Accession NZ_AP012541
Organism Lacticaseibacillus paracasei subsp. paracasei JCM 8130

Toxin (Protein)


Gene name yafQ Uniprot ID C2FG57
Locus tag LBPC_RS06155 Protein ID WP_003661092.1
Coordinates 1229595..1229897 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A8E0I752
Locus tag LBPC_RS06150 Protein ID WP_016365698.1
Coordinates 1229333..1229602 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBPC_RS15400 1225134..1225973 + 840 WP_081038465.1 hypothetical protein -
LBPC_RS15405 1226798..1227421 + 624 WP_079351422.1 hypothetical protein -
LBPC_RS06140 1227446..1228261 + 816 WP_003661098.1 DUF2399 domain-containing protein -
LBPC_RS06145 1228306..1228959 + 654 WP_003570049.1 GNAT family N-acetyltransferase -
LBPC_RS06150 1229333..1229602 + 270 WP_016365698.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LBPC_RS06155 1229595..1229897 + 303 WP_003661092.1 type II toxin-antitoxin system YafQ family toxin Toxin
LBPC_RS06160 1230497..1231189 + 693 WP_003661089.1 hypothetical protein -
LBPC_RS06165 1231425..1233602 + 2178 WP_016383421.1 RNA-binding transcriptional accessory protein -
LBPC_RS06170 1233777..1234214 - 438 WP_003661085.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-97)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(10-70)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11383.23 Da        Isoelectric Point: 10.4225

>T30560 WP_003661092.1 NZ_AP012541:1229595-1229897 [Lacticaseibacillus paracasei subsp. paracasei JCM 8130]
MYSLVPTPTFKRDLKRLSKKHWPMDELKTAVNLLAAGTNAELLSKKYADHALSSSSEWKGYRELHVDGPRGGWLLIYKIK
QQDLILTLVRTGSHHNLLGK

Download         Length: 303 bp

>T30560 NZ_AP012541:1229595-1229897 [Lacticaseibacillus paracasei subsp. paracasei JCM 8130]
ATGTATAGTCTGGTTCCGACGCCTACATTTAAGCGCGATCTAAAACGACTCTCCAAGAAGCATTGGCCGATGGACGAACT
AAAGACGGCTGTTAATCTCCTAGCTGCTGGTACAAATGCTGAACTATTAAGCAAAAAGTATGCAGATCATGCCTTGTCTT
CAAGCAGCGAGTGGAAAGGATATCGTGAACTACATGTTGACGGCCCTCGTGGCGGCTGGTTGCTAATCTATAAAATTAAG
CAGCAAGATCTTATTTTAACCCTAGTTAGAACCGGATCTCATCATAACCTTCTGGGTAAATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9996.71 Da        Isoelectric Point: 7.2026

>AT30560 WP_016365698.1 NZ_AP012541:1229333-1229602 [Lacticaseibacillus paracasei subsp. paracasei JCM 8130]
MAATKKETRLNIRIDPELKSAAQIVANDMGIDLTAAVTMFMTKMVKDHALPFTPTSLPVETLQALKEAKHPELLKKYSTP
DDMWRDLNV

Download         Length: 270 bp

>AT30560 NZ_AP012541:1229333-1229602 [Lacticaseibacillus paracasei subsp. paracasei JCM 8130]
ATGGCAGCCACAAAGAAAGAAACTCGCTTGAATATTCGTATTGATCCTGAATTAAAAAGTGCTGCTCAAATCGTAGCAAA
TGATATGGGCATCGACTTGACCGCAGCTGTTACGATGTTCATGACGAAAATGGTGAAGGATCACGCCCTCCCGTTTACCC
CAACAAGTCTACCAGTTGAAACCTTACAGGCGCTGAAAGAAGCAAAGCACCCAGAGCTGCTCAAAAAATACAGCACACCT
GATGACATGTGGAGAGACTTGAATGTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References