Detailed information of TA system TA030553

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2036077..2036323
• Replicon: chromosome
• Accession: NZ_AP012496
• Organism: Bacillus subtilis BEST7003

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: BEST7003_RS22105
• Protein ID: WP_109789044.1
• Coordinates: 2036077..2036169 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2036150..2036323 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BEST7003_RS09875	2031236..2031571	+	336	WP_009967409.1	hypothetical protein	-
BEST7003_RS09880	2031618..2035223	-	3606	WP_004399367.1	membrane protein	-
BEST7003_RS09885	2035456..2035788	-	333	WP_026009814.1	hypothetical protein	-
BEST7003_RS22105	2036077..2036169	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2036150..2036323	-	174	-	-	Antitoxin
BEST7003_RS09890	2036438..2037280	-	843	WP_003231327.1	hypothetical protein	-
BEST7003_RS09895	2037480..2037938	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
BEST7003_RS09900	2037948..2039750	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
BEST7003_RS09905	2039852..2040409	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2022472..2045740	23268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T30553 WP_109789044.1 NZ_AP012496:2036077-2036169 [Bacillus subtilis BEST7003]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T30553 NZ_AP012496:2036077-2036169 [Bacillus subtilis BEST7003]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT30553 NZ_AP012496:c2036323-2036150 [Bacillus subtilis BEST7003]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin