Detailed information of TA system TA030414

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 2535800..2536503
• Replicon: chromosome
• Accession: NC_023065
• Organism: Magnetospirillum gryphiswaldense MSR-1 v2

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: V6F2G1
• Locus tag: MGMSRV2_RS11960
• Protein ID: WP_011899495.1
• Coordinates: 2535800..2536096 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: V6F284
• Locus tag: MGMSRV2_RS11965
• Protein ID: WP_011899496.1
• Coordinates: 2536093..2536503 (+)
• Length: 137 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MGMSRV2_RS11925	2531497..2532696	+	1200	WP_011899488.1	hypothetical protein	-
MGMSRV2_RS11930	2532801..2533097	+	297	WP_024080626.1	thermonuclease family protein	-
MGMSRV2_RS11935	2533330..2533644	+	315	WP_011899490.1	hypothetical protein	-
MGMSRV2_RS11940	2533744..2534052	+	309	WP_024080627.1	hypothetical protein	-
MGMSRV2_RS11945	2534049..2534600	+	552	WP_011899492.1	hypothetical protein	-
MGMSRV2_RS11950	2534603..2534968	+	366	WP_024080628.1	hypothetical protein	-
MGMSRV2_RS11955	2535161..2535709	+	549	WP_024080629.1	M48 family metalloprotease	-
MGMSRV2_RS11960	2535800..2536096	+	297	WP_011899495.1	type II toxin-antitoxin system MqsR family toxin	Toxin
MGMSRV2_RS11965	2536093..2536503	+	411	WP_011899496.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
MGMSRV2_RS11970	2536607..2536864	-	258	WP_024080630.1	hypothetical protein	-
MGMSRV2_RS11975	2536932..2538506	-	1575	WP_011899498.1	recombinase family protein	-
MGMSRV2_RS11980	2538821..2539291	+	471	WP_024080155.1	translesion error-prone DNA polymerase V autoproteolytic subunit	-
MGMSRV2_RS11985	2539298..2540575	+	1278	WP_011899500.1	Y-family DNA polymerase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2501808..2554484	52676

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Antitoxin MqsA (6-129)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11094.74 Da
• Isoelectric Point: 9.5919

>T30414 WP_011899495.1 NC_023065:2535800-2536096 [Magnetospirillum gryphiswaldense MSR-1 v2]
MEKKRPTYALDTFKAAAKTLSVTVSATKDAGAMGFDRDGISAVIKNMEVGHFYKSMTSYNNNREWQDVYHVPYGGLVLYV
KFVADVVTEFRLLSFKEK

Nucleotide

• Length: 297 bp

>T30414 NC_023065:2535800-2536096 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGGAAAAGAAGCGCCCCACATACGCCCTCGACACCTTCAAGGCCGCCGCCAAGACCTTGAGTGTGACCGTTTCCGCCAC
CAAAGATGCGGGTGCGATGGGCTTTGATCGAGACGGCATCAGCGCCGTGATCAAGAACATGGAGGTCGGGCACTTCTACA
AGTCGATGACCAGCTATAACAATAACCGGGAATGGCAGGACGTTTATCACGTTCCCTATGGCGGGTTGGTTCTCTATGTG
AAATTCGTGGCCGATGTGGTCACCGAATTTCGTCTGCTGTCTTTCAAGGAGAAATGA

Antitoxin

Protein

• Length: 137 a.a.
• Molecular weight: 15038.26 Da
• Isoelectric Point: 7.6689

>AT30414 WP_011899496.1 NC_023065:2536093-2536503 [Magnetospirillum gryphiswaldense MSR-1 v2]
MTMATCHECGAEMVRDIRPMEFTYKGHTLTVQQPGWYCACGEGVLTPEDSAVTQAEYVAFRDQVDGILPPAEVRRIRKRL
GLQQKQAGVVLGGGASAFGKYERKDGKPSLAMSNLLRLLDKDPSRLQEIAPEEKRA

Nucleotide

• Length: 411 bp

>AT30414 NC_023065:2536093-2536503 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGACCATGGCGACGTGTCATGAATGCGGCGCGGAAATGGTTCGCGACATCCGGCCCATGGAGTTCACCTATAAGGGCCA
CACTCTGACCGTTCAGCAGCCGGGGTGGTATTGCGCTTGTGGTGAGGGCGTTCTGACCCCCGAGGACAGTGCCGTCACCC
AGGCGGAGTATGTTGCTTTCCGCGATCAGGTGGATGGCATCTTGCCTCCCGCAGAGGTTCGGCGCATTCGTAAGCGCCTG
GGCTTGCAGCAGAAACAGGCCGGTGTGGTTCTCGGCGGTGGCGCTTCGGCATTCGGTAAATATGAGCGCAAGGACGGCAA
GCCGTCGCTGGCCATGTCCAACTTGCTGCGTCTTCTGGACAAGGACCCCAGCCGCTTGCAGGAGATCGCGCCGGAAGAGA
AACGCGCCTGA

Structures

Toxin

• AlphaFold DB: V6F2G1

Antitoxin

• AlphaFold DB: V6F284