Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2395149..2395333 Replicon chromosome
Accession NC_022443
Organism Staphylococcus aureus subsp. aureus SA40

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SA40_RS11960 Protein ID WP_000482647.1
Coordinates 2395226..2395333 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2395149..2395209 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA40_RS11940 2390659..2390826 - 168 WP_031845053.1 hypothetical protein -
SA40_RS11950 2391057..2392790 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
SA40_RS11955 2392866..2394578 - 1713 WP_001064821.1 ABC transporter ATP-binding protein/permease -
- 2395149..2395209 + 61 - - Antitoxin
SA40_RS11960 2395226..2395333 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SA40_RS11965 2395466..2395852 - 387 WP_000779353.1 flippase GtxA -
SA40_RS11970 2396120..2397262 + 1143 WP_001176863.1 glycerate kinase -
SA40_RS11975 2397322..2397981 + 660 WP_000831298.1 membrane protein -
SA40_RS11980 2398164..2399375 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
SA40_RS11985 2399498..2399971 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T30134 WP_000482647.1 NC_022443:c2395333-2395226 [Staphylococcus aureus subsp. aureus SA40]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T30134 NC_022443:c2395333-2395226 [Staphylococcus aureus subsp. aureus SA40]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT30134 NC_022443:2395149-2395209 [Staphylococcus aureus subsp. aureus SA40]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References