Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2108312..2108575 Replicon chromosome
Accession NC_022443
Organism Staphylococcus aureus subsp. aureus SA40

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA40_RS10450 Protein ID WP_001802298.1
Coordinates 2108471..2108575 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2108312..2108476 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA40_RS10430 2104549..2105214 - 666 WP_001024088.1 SDR family oxidoreductase -
SA40_RS10435 2105366..2105686 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA40_RS10440 2105688..2106665 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
SA40_RS10445 2106931..2108022 + 1092 WP_000495695.1 hypothetical protein -
- 2108312..2108476 + 165 - - Antitoxin
SA40_RS10450 2108471..2108575 - 105 WP_001802298.1 hypothetical protein Toxin
SA40_RS14490 2108736..2109219 - 484 Protein_1966 recombinase family protein -
SA40_RS14185 2109262..2110398 - 1137 Protein_1967 SAP domain-containing protein -
SA40_RS10470 2110687..2110779 + 93 WP_031844941.1 hypothetical protein -
SA40_RS10475 2111474..2112331 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
SA40_RS10480 2112399..2113181 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T30131 WP_001802298.1 NC_022443:c2108575-2108471 [Staphylococcus aureus subsp. aureus SA40]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T30131 NC_022443:c2108575-2108471 [Staphylococcus aureus subsp. aureus SA40]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT30131 NC_022443:2108312-2108476 [Staphylococcus aureus subsp. aureus SA40]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References