Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2456325..2456509 Replicon chromosome
Accession NC_022442
Organism Staphylococcus aureus subsp. aureus SA957

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SA957_RS12390 Protein ID WP_000482647.1
Coordinates 2456402..2456509 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2456325..2456385 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA957_RS12370 2451835..2452002 - 168 WP_031845053.1 hypothetical protein -
SA957_RS12380 2452233..2453966 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
SA957_RS12385 2454042..2455754 - 1713 WP_001064821.1 ABC transporter ATP-binding protein/permease -
- 2456325..2456385 + 61 - - Antitoxin
SA957_RS12390 2456402..2456509 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SA957_RS12395 2456642..2457028 - 387 WP_000779353.1 flippase GtxA -
SA957_RS12400 2457296..2458438 + 1143 WP_001176863.1 glycerate kinase -
SA957_RS12405 2458498..2459157 + 660 WP_000831298.1 membrane protein -
SA957_RS12410 2459340..2460551 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
SA957_RS12415 2460674..2461147 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T30124 WP_000482647.1 NC_022442:c2456509-2456402 [Staphylococcus aureus subsp. aureus SA957]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T30124 NC_022442:c2456509-2456402 [Staphylococcus aureus subsp. aureus SA957]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT30124 NC_022442:2456325-2456385 [Staphylococcus aureus subsp. aureus SA957]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References