Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2169550..2169813 Replicon chromosome
Accession NC_022442
Organism Staphylococcus aureus subsp. aureus SA957

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA957_RS10880 Protein ID WP_001802298.1
Coordinates 2169709..2169813 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2169550..2169714 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA957_RS10860 2165787..2166452 - 666 WP_001024088.1 SDR family oxidoreductase -
SA957_RS10865 2166604..2166924 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA957_RS10870 2166926..2167903 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
SA957_RS10875 2168169..2169260 + 1092 WP_000495695.1 hypothetical protein -
- 2169550..2169714 + 165 - - Antitoxin
SA957_RS10880 2169709..2169813 - 105 WP_001802298.1 hypothetical protein Toxin
SA957_RS14995 2169974..2170457 - 484 Protein_2060 recombinase family protein -
SA957_RS14675 2170500..2171636 - 1137 Protein_2061 SAP domain-containing protein -
SA957_RS10900 2171925..2172017 + 93 WP_031844941.1 hypothetical protein -
SA957_RS10905 2172712..2173569 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
SA957_RS10910 2173637..2174419 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-137)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T30122 WP_001802298.1 NC_022442:c2169813-2169709 [Staphylococcus aureus subsp. aureus SA957]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T30122 NC_022442:c2169813-2169709 [Staphylococcus aureus subsp. aureus SA957]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT30122 NC_022442:2169550-2169714 [Staphylococcus aureus subsp. aureus SA957]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References