Detailed information of TA system TA029964

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 2440777..2441300
• Replicon: chromosome
• Accession: NC_022222
• Organism: Staphylococcus aureus subsp. aureus 6850

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: RSAU_RS12320
• Protein ID: WP_042908766.1
• Coordinates: 2440777..2441043 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: RSAU_RS12325
• Protein ID: WP_020977565.1
• Coordinates: 2441043..2441300 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (28-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10638.34 Da
• Isoelectric Point: 10.0798

>T29964 WP_042908766.1 NC_022222:c2441043-2440777 [Staphylococcus aureus subsp. aureus 6850]
MSNYTVKIKNSAKLDLKKIKHPYLKKTFIEIVETLKNDPCKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLI
LSAWSHYD

Nucleotide

• Length: 267 bp

>T29964 NC_022222:c2441043-2440777 [Staphylococcus aureus subsp. aureus 6850]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAGTTAGATTTAAAGAAAATAAAACATCCTTATTTAAAGAAGAC
ATTTATAGAAATTGTTGAGACTTTAAAAAATGATCCTTGTAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9796.79 Da
• Isoelectric Point: 4.3304

>AT29964 WP_020977565.1 NC_022222:c2441300-2441043 [Staphylococcus aureus subsp. aureus 6850]
MIITSPTEARKHFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDI
DWDNL

Nucleotide

• Length: 258 bp

>AT29964 NC_022222:c2441300-2441043 [Staphylococcus aureus subsp. aureus 6850]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAGCATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTCAGAGAAAGAGAAAAAGATAATAGTGGTACTACAAATATAGACGATATT
GATTGGGATAATCTTTAA