Detailed information of TA system TA029959

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2116805..2117022
• Replicon: chromosome
• Accession: NC_022222
• Organism: Staphylococcus aureus subsp. aureus 6850

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: RSAU_RS10615
• Protein ID: WP_001802298.1
• Coordinates: 2116918..2117022 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2116805..2116860 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSAU_RS10595	2112938..2113603	-	666	WP_001024095.1	SDR family oxidoreductase	-
RSAU_RS10600	2113755..2114075	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
RSAU_RS10605	2114077..2115054	+	978	WP_000019732.1	CDF family zinc efflux transporter CzrB	-
RSAU_RS10610	2115320..2116411	+	1092	WP_020977458.1	hypothetical protein	-
-	2116805..2116860	+	56	-	-	Antitoxin
RSAU_RS10615	2116918..2117022	-	105	WP_001802298.1	hypothetical protein	Toxin
RSAU_RS14605	2117183..2117686	-	504	Protein_2007	recombinase family protein	-
RSAU_RS10625	2117734..2119026	+	1293	WP_020977460.1	IS21 family transposase	-
RSAU_RS10630	2119019..2119780	+	762	WP_001066124.1	IS21-like element helper ATPase IstB	-
RSAU_RS14685	2119916..2121052	-	1137	Protein_2010	SAP domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2119016..2119780	764

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T29959 WP_001802298.1 NC_022222:c2117022-2116918 [Staphylococcus aureus subsp. aureus 6850]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T29959 NC_022222:c2117022-2116918 [Staphylococcus aureus subsp. aureus 6850]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT29959 NC_022222:2116805-2116860 [Staphylococcus aureus subsp. aureus 6850]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin