Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2116805..2117022 Replicon chromosome
Accession NC_022222
Organism Staphylococcus aureus subsp. aureus 6850

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RSAU_RS10615 Protein ID WP_001802298.1
Coordinates 2116918..2117022 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2116805..2116860 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RSAU_RS10595 2112938..2113603 - 666 WP_001024095.1 SDR family oxidoreductase -
RSAU_RS10600 2113755..2114075 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RSAU_RS10605 2114077..2115054 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
RSAU_RS10610 2115320..2116411 + 1092 WP_020977458.1 hypothetical protein -
- 2116805..2116860 + 56 - - Antitoxin
RSAU_RS10615 2116918..2117022 - 105 WP_001802298.1 hypothetical protein Toxin
RSAU_RS14605 2117183..2117686 - 504 Protein_2007 recombinase family protein -
RSAU_RS10625 2117734..2119026 + 1293 WP_020977460.1 IS21 family transposase -
RSAU_RS10630 2119019..2119780 + 762 WP_001066124.1 IS21-like element helper ATPase IstB -
RSAU_RS14685 2119916..2121052 - 1137 Protein_2010 SAP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2119016..2119780 764


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T29959 WP_001802298.1 NC_022222:c2117022-2116918 [Staphylococcus aureus subsp. aureus 6850]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29959 NC_022222:c2117022-2116918 [Staphylococcus aureus subsp. aureus 6850]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT29959 NC_022222:2116805-2116860 [Staphylococcus aureus subsp. aureus 6850]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References