Detailed information of TA system TA029953

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1805125..1805305
• Replicon: chromosome
• Accession: NC_022222
• Organism: Staphylococcus aureus subsp. aureus 6850

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RSAU_RS14565
• Protein ID: WP_001801861.1
• Coordinates: 1805125..1805220 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1805248..1805305 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSAU_RS08795	1800592..1801587	+	996	WP_020977362.1	DUF4352 domain-containing protein	-
RSAU_RS08800	1801663..1802289	+	627	WP_000669045.1	hypothetical protein	-
RSAU_RS08805	1802330..1802671	+	342	WP_000627534.1	DUF3969 family protein	-
RSAU_RS08810	1802772..1803344	+	573	WP_000414218.1	hypothetical protein	-
RSAU_RS08815	1803674..1803859	-	186	WP_000809860.1	hypothetical protein	-
RSAU_RS08820	1803861..1804037	-	177	WP_000375478.1	hypothetical protein	-
RSAU_RS08825	1804048..1804337	-	290	Protein_1697	hypothetical protein	-
RSAU_RS08830	1804505..1804738	-	234	Protein_1698	IS3 family transposase	-
RSAU_RS08835	1804744..1804980	-	237	WP_000251969.1	IS3 family transposase	-
RSAU_RS14565	1805125..1805220	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1805248..1805305	-	58	-	-	Antitoxin
RSAU_RS08840	1806161..1806604	-	444	WP_000728661.1	DUF1433 domain-containing protein	-
RSAU_RS08845	1806604..1807047	-	444	WP_000731420.1	DUF1433 domain-containing protein	-
RSAU_RS08850	1807047..1807490	-	444	WP_000747798.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1804744..1804980	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29953 WP_001801861.1 NC_022222:1805125-1805220 [Staphylococcus aureus subsp. aureus 6850]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29953 NC_022222:1805125-1805220 [Staphylococcus aureus subsp. aureus 6850]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29953 NC_022222:c1805305-1805248 [Staphylococcus aureus subsp. aureus 6850]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin