Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2444326..2444510 Replicon chromosome
Accession NC_022113
Organism Staphylococcus aureus subsp. aureus 55/2053

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag SAAG_RS12395 Protein ID WP_000482648.1
Coordinates 2444403..2444510 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2444326..2444386 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAAG_RS12370 2439836..2440003 - 168 Protein_2357 hypothetical protein -
SAAG_RS12380 2440234..2441967 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
SAAG_RS12385 2441992..2443755 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2444326..2444386 + 61 - - Antitoxin
SAAG_RS12395 2444403..2444510 - 108 WP_000482648.1 type I toxin-antitoxin system Fst family toxin Toxin
SAAG_RS12400 2444644..2445030 - 387 WP_000779351.1 flippase GtxA -
SAAG_RS12405 2445298..2446440 + 1143 WP_001176855.1 glycerate kinase -
SAAG_RS12410 2446500..2447159 + 660 WP_000831298.1 membrane protein -
SAAG_RS12415 2447341..2448552 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
SAAG_RS12420 2448675..2449148 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4026.79 Da        Isoelectric Point: 10.4935

>T29935 WP_000482648.1 NC_022113:c2444510-2444403 [Staphylococcus aureus subsp. aureus 55/2053]
MFNLLIEIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T29935 NC_022113:c2444510-2444403 [Staphylococcus aureus subsp. aureus 55/2053]
ATGTTCAATTTATTAATTGAAATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT29935 NC_022113:2444326-2444386 [Staphylococcus aureus subsp. aureus 55/2053]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References