Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2159228..2159444 Replicon chromosome
Accession NC_022113
Organism Staphylococcus aureus subsp. aureus 55/2053

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag SAAG_RS10885 Protein ID WP_073392962.1
Coordinates 2159340..2159444 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2159228..2159283 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAAG_RS10865 2155422..2156087 - 666 WP_001024099.1 SDR family oxidoreductase -
SAAG_RS10870 2156239..2156559 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAAG_RS10875 2156561..2157541 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
SAAG_RS10880 2157807..2158898 + 1092 WP_000495684.1 hypothetical protein -
- 2159228..2159283 + 56 - - Antitoxin
SAAG_RS10885 2159340..2159444 - 105 WP_073392962.1 hypothetical protein Toxin
SAAG_RS14620 2160124..2160282 + 159 WP_001792784.1 hypothetical protein -
SAAG_RS10890 2160941..2161798 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
SAAG_RS10895 2161866..2162648 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T29932 WP_073392962.1 NC_022113:c2159444-2159340 [Staphylococcus aureus subsp. aureus 55/2053]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29932 NC_022113:c2159444-2159340 [Staphylococcus aureus subsp. aureus 55/2053]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT29932 NC_022113:2159228-2159283 [Staphylococcus aureus subsp. aureus 55/2053]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References