Detailed information of TA system TA029924

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1827608..1827788
• Replicon: chromosome
• Accession: NC_022113
• Organism: Staphylococcus aureus subsp. aureus 55/2053

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAAG_RS14885
• Protein ID: WP_001801861.1
• Coordinates: 1827608..1827703 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1827731..1827788 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAAG_RS08855	1822752..1823378	+	627	WP_000669038.1	hypothetical protein	-
SAAG_RS08860	1823419..1823763	+	345	WP_000627550.1	DUF3969 family protein	-
SAAG_RS08865	1823861..1824433	+	573	WP_000414222.1	hypothetical protein	-
SAAG_RS08870	1824582..1825949	-	1368	WP_001093574.1	FRG domain-containing protein	-
SAAG_RS08875	1825949..1826518	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
SAAG_RS08880	1826711..1827157	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
SAAG_RS14885	1827608..1827703	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1827731..1827788	-	58	-	-	Antitoxin
SAAG_RS08885	1827826..1827927	+	102	WP_001791232.1	hypothetical protein	-
SAAG_RS08890	1828102..1828545	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
SAAG_RS08895	1828545..1828988	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
SAAG_RS14480	1828988..1829430	-	443	Protein_1728	DUF1433 domain-containing protein	-
SAAG_RS08905	1829955..1832375	+	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (8-85)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29924 WP_001801861.1 NC_022113:1827608-1827703 [Staphylococcus aureus subsp. aureus 55/2053]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29924 NC_022113:1827608-1827703 [Staphylococcus aureus subsp. aureus 55/2053]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29924 NC_022113:c1827788-1827731 [Staphylococcus aureus subsp. aureus 55/2053]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin