Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 9630..10135 Replicon plasmid SF2022_p1
Accession NZ_OX460977
Organism Carnobacterium maltaromaticum strain SF2022 isolate SF2022

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1X6WJQ1
Locus tag QOS94_RS15795 Protein ID WP_022797157.1
Coordinates 9630..9896 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID U5SCD4
Locus tag QOS94_RS15800 Protein ID WP_010620828.1
Coordinates 9881..10135 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS94_RS15780 5383..5967 - 585 WP_229252455.1 recombinase family protein -
QOS94_RS15785 6152..9157 + 3006 WP_084679661.1 Tn3 family transposase -
QOS94_RS15790 9167..9310 - 144 WP_015076903.1 hypothetical protein -
QOS94_RS15795 9630..9896 - 267 WP_022797157.1 Txe/YoeB family addiction module toxin Toxin
QOS94_RS15800 9881..10135 - 255 WP_010620828.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QOS94_RS15805 10796..11368 + 573 WP_002292150.1 DNA starvation/stationary phase protection protein -
QOS94_RS15810 11513..12217 + 705 WP_002293764.1 Crp/Fnr family transcriptional regulator -
QOS94_RS15815 12446..12784 + 339 WP_002300938.1 hypothetical protein -
QOS94_RS15820 12769..13416 + 648 WP_034558129.1 prolipoprotein diacylglyceryl transferase -
QOS94_RS15825 13563..13796 + 234 WP_003103602.1 heavy-metal-associated domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..92683 92683


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.06 Da        Isoelectric Point: 9.8673

>T297042 WP_022797157.1 NZ_OX460977:c9896-9630 [Carnobacterium maltaromaticum]
MGYSIKLAKSTMKDLKNLKSAHLEQKFKDIMEILKENPFQNPPPYEKLVGNLKDNYSRRLNIQHRVVYSVDNDAKEVIIW
SAWTHYER

Download         Length: 267 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9673.80 Da        Isoelectric Point: 4.1473

>AT297042 WP_010620828.1 NZ_OX460977:c10135-9881 [Carnobacterium maltaromaticum]
MSIVNPSQARKVFYQLLKDVNKTNEPIYISGKNEESEAVMVSKKDWDAIQETLYLQSAGVADVIHQREQENEFVALEDID
WDTL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X6WJQ1

Antitoxin

Source ID Structure
AlphaFold DB A0A1H6W4Y2

References