297037

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4697154..4697850 Replicon chromosome
Accession NZ_OX460963
Organism Hafnia paralvei strain MIP2461 isolate MIP2461

Toxin (Protein)


Gene name mqsR Uniprot ID G9YDK7
Locus tag QOT00_RS21660 Protein ID WP_004096963.1
Coordinates 4697539..4697850 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag QOT00_RS21655 Protein ID WP_223283572.1
Coordinates 4697154..4697555 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT00_RS21640 4693896..4694738 + 843 WP_130996012.1 helix-turn-helix domain-containing protein -
QOT00_RS21645 4695055..4695342 + 288 WP_008815650.1 PapB/FocB family fimbrial expression transcriptional regulator -
QOT00_RS21650 4695424..4696911 - 1488 WP_004096959.1 glycerol-3-phosphate dehydrogenase -
QOT00_RS21655 4697154..4697555 - 402 WP_223283572.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
QOT00_RS21660 4697539..4697850 - 312 WP_004096963.1 type II toxin-antitoxin system MqsR family toxin Toxin
QOT00_RS21665 4698100..4698858 - 759 WP_004096965.1 DeoR/GlpR family transcriptional regulator -
QOT00_RS21670 4698892..4699728 - 837 WP_039186087.1 rhomboid family intramembrane serine protease GlpG -
QOT00_RS21675 4699881..4700210 - 330 WP_008815654.1 thiosulfate sulfurtransferase GlpE -
QOT00_RS21680 4700484..4700918 + 435 WP_283648223.1 hypothetical protein -
QOT00_RS21685 4701594..4702337 - 744 WP_008815656.1 glycerophosphodiester phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA/HigA-2

(2-132)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12128.96 Da        Isoelectric Point: 9.0652

>T297037 WP_004096963.1 NZ_OX460963:c4697850-4697539 [Hafnia paralvei]
MEKRTPHCRLEKIRSLIGKGLIRATALSSRNARQLNFSRADMYRIVSELSTQDFHKSMTTYENHRVWQDVYHCHLDKVSL
YVKLTVIDEVLIVSFKELNDDMS

Download         Length: 312 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14799.14 Da        Isoelectric Point: 4.9471

>AT297037 WP_223283572.1 NZ_OX460963:c4697555-4697154 [Hafnia paralvei]
MMICPECGSVNTVKEYRDMPYTYKGQTIIVKAVGADWCLNCGEGVVFTEESIRIDSIMGDFNKQVNASIIEPEFVIAMRK
KLNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLAEIRD

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G9YDK7

Antitoxin

Source ID Structure

References