Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 902597..903195 Replicon chromosome
Accession NZ_OX460951
Organism Morganella morganii strain HIS2824 isolate HIS2824

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QOS63_RS04045 Protein ID WP_046895229.1
Coordinates 902597..902875 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QOS63_RS04050 Protein ID WP_283623448.1
Coordinates 902875..903195 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS63_RS04040 899962..902466 + 2505 WP_283623447.1 bifunctional glycosyl transferase/transpeptidase -
QOS63_RS04045 902597..902875 + 279 WP_046895229.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOS63_RS04050 902875..903195 + 321 WP_283623448.1 HigA family addiction module antitoxin Antitoxin
QOS63_RS04055 903255..903911 - 657 WP_052926391.1 formate dehydrogenase-N subunit gamma -
QOS63_RS04060 903904..904794 - 891 WP_052926392.1 formate dehydrogenase subunit beta -
QOS63_RS04065 904804..907851 - 3048 WP_218455096.1 formate dehydrogenase-N subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(7-81)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10679.27 Da        Isoelectric Point: 8.5628

>T297020 WP_046895229.1 NZ_OX460951:902597-902875 [Morganella morganii]
MIKSFKHKGLKQLFENGVISGIPAQDAVRINDRLQAIDSATMIEDLNIHIYKLHPLRGDRVGIWSITVRANWRITFEFRN
GDAYILNLEDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11307.00 Da        Isoelectric Point: 9.0498

>AT297020 WP_283623448.1 NZ_OX460951:902875-903195 [Morganella morganii]
MKQAIVSHPGTIVANILTDLGVGVRQFAGNIGVTPATVSRFLSGKTALTPALAIRIAAALGSNPAFWLRLQANYDLHRLE
KEIDISGIKLYGASEEDGFCNRSPDK

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References