296992

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 502222..502874 Replicon chromosome
Accession NZ_OX460909
Organism Photobacterium phosphoreum strain MIP2473 isolate MIP2473

Toxin (Protein)


Gene name higB Uniprot ID A0A2T3M7R5
Locus tag QOS47_RS02550 Protein ID WP_045032861.1
Coordinates 502527..502874 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QOS47_RS02545 Protein ID WP_045032858.1
Coordinates 502222..502524 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS47_RS02505 497832..498176 + 345 WP_045032219.1 hypothetical protein -
QOS47_RS02510 498287..498520 - 234 WP_045032221.1 hypothetical protein -
QOS47_RS02515 499058..499300 + 243 WP_045032924.1 hypothetical protein -
QOS47_RS02520 499555..500706 + 1152 WP_107188197.1 iron-containing alcohol dehydrogenase -
QOS47_RS02530 501400..501675 - 276 WP_232605835.1 helix-turn-helix transcriptional regulator -
QOS47_RS02535 501672..501794 - 123 WP_232613877.1 type II toxin-antitoxin system RelE/ParE family toxin -
QOS47_RS02540 501799..501978 - 180 WP_268875251.1 type II toxin-antitoxin system RelE/ParE family toxin -
QOS47_RS02545 502222..502524 - 303 WP_045032858.1 helix-turn-helix transcriptional regulator Antitoxin
QOS47_RS02550 502527..502874 - 348 WP_045032861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOS47_RS02555 503327..503605 - 279 WP_283597067.1 hypothetical protein -
QOS47_RS02560 503841..504365 - 525 WP_283597070.1 heavy metal-binding domain-containing protein -
QOS47_RS02565 505038..505280 + 243 WP_045032924.1 hypothetical protein -
QOS47_RS02570 505535..506686 + 1152 WP_283597072.1 iron-containing alcohol dehydrogenase -
QOS47_RS02575 506778..506990 - 213 WP_045029221.1 cold-shock protein -
QOS47_RS02580 507294..507746 - 453 Protein_471 DUF2333 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-81)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13108.92 Da        Isoelectric Point: 5.1769

>T296992 WP_045032861.1 NZ_OX460909:c502874-502527 [Photobacterium phosphoreum]
MWTVITTDFFDEWFDAQSDDTQEKVLAGLVALQTGGPTIGRPLVDTVNASKYNNMKELRVQHRGDPIRAFFAFDPLRQAI
VLCAGNKGGNEKRFYKQMIPIADFEFAKHLEELEK

Download         Length: 348 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11214.90 Da        Isoelectric Point: 5.7202

>AT296992 WP_045032858.1 NZ_OX460909:c502524-502222 [Photobacterium phosphoreum]
MARNLNDMLASRSQDSQHRIAEMADEMLLEVKFQAIREELELTQAELARNMGISQPSVVAIEQRGNDVKLSTIKRYIEAM
GGKMSINIELPTGKHVGFNV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T3M7R5

Antitoxin

Source ID Structure

References