Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-SR6/-
Location 2269537..2269826 Replicon chromosome
Accession NZ_OX419579
Organism Bacillus subtilis isolate NRS6103

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag KJP43_RS11685 Protein ID WP_009967548.1
Coordinates 2269537..2269653 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2269648..2269826 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP43_RS11655 (2264997) 2264997..2266235 - 1239 WP_142743355.1 MFS transporter -
KJP43_RS11660 (2266348) 2266348..2267598 - 1251 WP_153912306.1 UV damage repair protein UvrX -
KJP43_RS11665 (2267591) 2267591..2267923 - 333 WP_128473977.1 YolD-like family protein -
KJP43_RS11670 (2268097) 2268097..2268432 + 336 WP_004399073.1 hypothetical protein -
KJP43_RS11675 (2268475) 2268475..2268831 - 357 WP_019712874.1 hypothetical protein -
KJP43_RS11680 (2268837) 2268837..2269304 - 468 WP_128992107.1 DUF4879 domain-containing protein -
KJP43_RS11685 (2269537) 2269537..2269653 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2269648) 2269648..2269826 - 179 NuclAT_1 - Antitoxin
- (2269648) 2269648..2269826 - 179 NuclAT_1 - Antitoxin
- (2269648) 2269648..2269826 - 179 NuclAT_1 - Antitoxin
- (2269648) 2269648..2269826 - 179 NuclAT_1 - Antitoxin
KJP43_RS11690 (2270277) 2270277..2270840 - 564 WP_250533594.1 SMI1/KNR4 family protein -
KJP43_RS11695 (2270854) 2270854..2271342 - 489 WP_041056186.1 antitoxin YezG family protein -
KJP43_RS11700 (2271349) 2271349..2273259 - 1911 WP_153912308.1 ribonuclease YeeF family protein -
KJP43_RS11705 (2273359) 2273359..2273916 - 558 WP_153912309.1 SMI1/KNR4 family protein -
KJP43_RS11710 (2273982) 2273982..2274235 - 254 Protein_2255 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2142959..2279223 136264


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T296924 WP_009967548.1 NZ_OX419579:2269537-2269653 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

Antitoxin


Download         Length: 179 bp

>AT296924 NZ_OX419579:c2269826-2269648 [Bacillus subtilis]
AATGATACAAATAATTATTTTTTGCATTTTGATTTGTAGAAATGCATAAAATAAAAAGACCAGGGTGCTACCAACACCCC
AGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCAGATGTATGTGACATAGTAGACCAACCCTTTAGGGTCGCAAT
CTCAAGGGGAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References