Detailed information of TA system TA296867

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2147211..2147457
• Replicon: chromosome
• Accession: NZ_OX419570
• Organism: Bacillus subtilis isolate NRS6134

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: KJP59_RS10880
• Protein ID: WP_109789044.1
• Coordinates: 2147211..2147303 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2147284..2147457 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJP59_RS10865	2142370..2142705	+	336	WP_009967409.1	hypothetical protein	-
KJP59_RS10870	2142752..2146357	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
KJP59_RS10875	2146590..2146922	-	333	WP_026009814.1	hypothetical protein	-
KJP59_RS10880	2147211..2147303	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2147284..2147457	-	174	-	-	Antitoxin
KJP59_RS10885	2147572..2148414	-	843	WP_003231327.1	hypothetical protein	-
KJP59_RS10890	2148614..2149072	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
KJP59_RS10895	2149082..2150884	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
KJP59_RS10900	2150986..2151543	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2133196..2156874	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T296867 WP_109789044.1 NZ_OX419570:2147211-2147303 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT296867 NZ_OX419570:c2147457-2147284 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin